ID   A0A239RHP2_9BACT        Unreviewed;       603 AA.
AC   A0A239RHP2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (Putrescine degradation), contains GATase1-like domain {ECO:0000313|EMBL:SNU10420.1};
GN   ORFNames=SAMN06298210_102182 {ECO:0000313|EMBL:SNU10420.1};
OS   Prevotellaceae bacterium KH2P17.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae.
OX   NCBI_TaxID=1945886 {ECO:0000313|EMBL:SNU10420.1, ECO:0000313|Proteomes:UP000214740};
RN   [1] {ECO:0000313|EMBL:SNU10420.1, ECO:0000313|Proteomes:UP000214740}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KH2P17 {ECO:0000313|EMBL:SNU10420.1,
RC   ECO:0000313|Proteomes:UP000214740};
RA   Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZRE01000002; SNU10420.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239RHP2; -.
DR   Proteomes; UP000214740; Unassembled WGS sequence.
DR   GO; GO:0070573; F:metallodipeptidase activity; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd01745; GATase1_2; 1.
DR   CDD; cd01301; rDP_like; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   InterPro; IPR008257; Pept_M19.
DR   InterPro; IPR011697; Peptidase_C26.
DR   PANTHER; PTHR10443:SF12; DIPEPTIDASE; 1.
DR   PANTHER; PTHR10443; MICROSOMAL DIPEPTIDASE; 1.
DR   Pfam; PF07722; Peptidase_C26; 1.
DR   Pfam; PF01244; Peptidase_M19; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
DR   PROSITE; PS51365; RENAL_DIPEPTIDASE_2; 1.
PE   4: Predicted;
KW   Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW   Hydrolase {ECO:0000313|EMBL:SNU10420.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000214740}.
FT   ACT_SITE        126
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT   ACT_SITE        232
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT   ACT_SITE        234
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ   SEQUENCE   603 AA;  66109 MW;  699C87B55FF30523 CRC64;
     MNDFDLQSHL DSVYATFPEA SNRPVIGITS NYTNGDAALR DRYYTQVVAA GGTPVIIPPV
     ADKDVIIGTL DRIDGLLLTG GGDYNPLWAG EEPLPQLHGI NSERDLPELL LTRLAFNRQI
     PMLGICRGIQ TLALALGGTL MQDIAQGMPA AARLLKHSQD ADRQEPTHSV SIEPDSILHG
     IYGAERLYVN SFHHQAVQDP GKRFRVTAQA PDGVTEAIES TEFKAVLGVQ WHPEWLQQEG
     LKLFEWLVGE AGNFSVAKRL HHRVLTLDTH CDTPMFFPQG VNFAQRDPRI LVDLHKMADG
     RQDAVTMVAY LPQPKPGEPF AEKIDIAGLQ KYNPQQAELL SHITPTAYAD FIFDKIEATV
     HEHAASVAIA RTPAQLYENK RHGRKSVMLG IENGLALGSD LSNISHFAQR GVVYITLCHN
     GDNQICDSAR GSGTHGGVSA FGEQVIREMN AQGIMVDLSH GAERSFYDAL DISQLPIVCS
     HSNCRALCNV PRNLTDQQLR ALALKGGVAH TTLYAGFLRQ AGEADIRDAV AHLEHAISVM
     GIEHVGLGTD FDGDGGIRGL ADSSELINFT ICLLRRKYSE QDIARIWGGN WLRVMTQVQN
     ARK
//