ID A0A239SVE3_9STRE Unreviewed; 337 AA.
AC A0A239SVE3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=LacI family transcriptional repressor {ECO:0000313|EMBL:SNU89202.1};
GN Name=malR {ECO:0000313|EMBL:SNU89202.1};
GN ORFNames=SAMEA4412692_01399 {ECO:0000313|EMBL:SNU89202.1};
OS Streptococcus merionis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=400065 {ECO:0000313|EMBL:SNU89202.1, ECO:0000313|Proteomes:UP000215185};
RN [1] {ECO:0000313|EMBL:SNU89202.1, ECO:0000313|Proteomes:UP000215185}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13788 {ECO:0000313|EMBL:SNU89202.1,
RC ECO:0000313|Proteomes:UP000215185};
RG Pathogen Informatics;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT906439; SNU89202.1; -; Genomic_DNA.
DR RefSeq; WP_018374237.1; NZ_LT906439.1.
DR AlphaFoldDB; A0A239SVE3; -.
DR STRING; 1123308.GCA_000380085_01701; -.
DR KEGG; smen:SAMEA4412692_1399; -.
DR eggNOG; COG1609; Bacteria.
DR OrthoDB; 9788209at2; -.
DR Proteomes; UP000215185; Chromosome 1.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06294; PBP1_MalR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000215185};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 337 AA; 37794 MW; 9D85F678A5DAE638 CRC64;
MVTIRDVAER AGVNASTVSR ALKDSSAISK KTKEKVKKAM AELGYVPNLA AKMLASGLTH
SIGVVFPPMT TRDTKSQPFH MEILTEINHT AKVHGYTISI ATGESTEDLK NQIHHMYLER
RVDGFILLYS FKNDPVQAHL LANKIPFVMV GTPVQDENET TYIDNDNQLM AKTAVQYLQE
KGHEQILFVT DNLDGEVQKA RYAGYLSGLE MLNLPSHQAL IFDRSRAETV AQLVQTVEEK
QATAFVVIDD MLSLRVSQLL SFYQLKVPDD ISIISFNNSA YAKIIHPYLT TFDVNIAALG
RTAFTRIFEK VQTKVDENAK VTVPFTLKER ESVRNRL
//
