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Database: UniProt
Entry: A0A239TL18_9FIRM
LinkDB: A0A239TL18_9FIRM
Original site: A0A239TL18_9FIRM 
ID   A0A239TL18_9FIRM        Unreviewed;       162 AA.
AC   A0A239TL18;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   10-APR-2019, entry version 5.
DE   RecName: Full=Mini-ribonuclease 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-RNase 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            EC=3.1.26.- {ECO:0000256|HAMAP-Rule:MF_01468};
DE   AltName: Full=Mini-RNase III {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-III {ECO:0000256|HAMAP-Rule:MF_01468};
GN   Name=mrnC {ECO:0000256|HAMAP-Rule:MF_01468,
GN   ECO:0000313|EMBL:SNU98507.1};
GN   ORFNames=SAMEA4364220_00941 {ECO:0000313|EMBL:SNU98507.1};
OS   Megamonas hypermegale.
OC   Bacteria; Firmicutes; Negativicutes; Selenomonadales;
OC   Selenomonadaceae; Megamonas.
OX   NCBI_TaxID=158847 {ECO:0000313|EMBL:SNU98507.1, ECO:0000313|Proteomes:UP000215383};
RN   [1] {ECO:0000313|EMBL:SNU98507.1, ECO:0000313|Proteomes:UP000215383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC10570 {ECO:0000313|EMBL:SNU98507.1,
RC   ECO:0000313|Proteomes:UP000215383};
RG   Pathogen Informatics;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in correct processing of both the 5' and 3'
CC       ends of 23S rRNA precursor. Processes 30S rRNA precursor
CC       transcript even in absence of ribonuclease 3 (Rnc); Rnc processes
CC       30S rRNA into smaller rRNA precursors. {ECO:0000256|HAMAP-
CC       Rule:MF_01468}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01468};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01468}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468}.
CC   -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000256|HAMAP-
CC       Rule:MF_01468}.
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DR   EMBL; LT906446; SNU98507.1; -; Genomic_DNA.
DR   RefSeq; WP_027890787.1; NZ_NFIW01000001.1.
DR   STRING; 1122216.AUHW01000004_gene1628; -.
DR   BioCyc; GCF_000423385:G1EGS-447-MONOMER; -.
DR   Proteomes; UP000215383; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   HAMAP; MF_01468; RNase_Mini_III; 1.
DR   InterPro; IPR008226; Mini3_fam.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00636; Ribonuclease_3; 1.
DR   PIRSF; PIRSF005520; UCP005520; 1.
DR   SUPFAM; SSF69065; SSF69065; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000215383};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Endonuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01468,
KW   ECO:0000313|EMBL:SNU98507.1};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215383};
KW   Ribosome biogenesis {ECO:0000256|HAMAP-Rule:MF_01468};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01468};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01468};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01468}.
FT   DOMAIN       40    136       RNase III. {ECO:0000259|Pfam:PF00636}.
FT   ACT_SITE     46     46       {ECO:0000256|HAMAP-Rule:MF_01468}.
SQ   SEQUENCE   162 AA;  19230 MW;  3848B0B8A54FE9C3 CRC64;
     MKFQQYQNLK KNLFPFNEQN VLNDRYKKED INPRQLNPLV LAYVGDAYYH LYIRTRLLNF
     EQAHVHLLND FSMQIVSATF QVQAYEAIKD ELTETESYIF KRGKNAKSHA PRVASVHDYH
     ISTGFEAILG YLYLNNEQNR LDFLCERSFL QVAKNMYQAH QQ
//
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