ID A0A239U120_9FIRM Unreviewed; 430 AA.
AC A0A239U120;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Aerobic C4-dicarboxylate transport protein {ECO:0000313|EMBL:SNV03329.1};
GN Name=dctA {ECO:0000313|EMBL:SNV03329.1};
GN ORFNames=SAMEA4364220_01752 {ECO:0000313|EMBL:SNV03329.1};
OS Megamonas hypermegale.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC Megamonas.
OX NCBI_TaxID=158847 {ECO:0000313|EMBL:SNV03329.1, ECO:0000313|Proteomes:UP000215383};
RN [1] {ECO:0000313|EMBL:SNV03329.1, ECO:0000313|Proteomes:UP000215383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10570 {ECO:0000313|EMBL:SNV03329.1,
RC ECO:0000313|Proteomes:UP000215383};
RG Pathogen Informatics;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LT906446; SNV03329.1; -; Genomic_DNA.
DR RefSeq; WP_027890042.1; NZ_LT906446.1.
DR AlphaFoldDB; A0A239U120; -.
DR GeneID; 78507743; -.
DR eggNOG; COG1301; Bacteria.
DR Proteomes; UP000215383; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF1; AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215383};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 41..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 430 AA; 45482 MW; D5CE6CE22AB686F4 CRC64;
MVAKIKSSLF LQVVLALILG LIVGVVFPTQ AQALKPLGDL FIRFIQLLIA PIVFCVVVNG
ISGVGNIKKV GTVGVKTIFY FECVTTIALA LGLVLGLNSN IGMGMNIDPS SLDASAISAY
TERAQTISQA GGVSFLMNLV PTTVVGAFAK GDILQVLVFS IIFACSLNLV KDKASIVVKA
VSELSTVFFR AMGIIVRFAP VGVFGAVAFT VGKYGLDSLG HLGALVGLYF VTCILFVIVV
LGGILRLCGI NLFQFLRYLR EELMIVFATT ASDSVLPQIM KKLENMGIKS STVGLVIPTG
YSFNLDGFSI YLTLATIFIA HATNVDLAFS DLLMIIIVSM IASKGAHGVP GSAIVILAAT
LSAIPAIPMI GLVLILSIDW FVGIARAVTN IIGNCVATVV IAKWEGDLDI EQAHEVLSSK
EKLQVQNAIH
//
