ID A0A239XC55_9SPHI Unreviewed; 631 AA.
AC A0A239XC55;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
GN ORFNames=SAMN05192578_103110 {ECO:0000313|EMBL:SDL38234.1};
OS Sphingobacterium mizutaii.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Sphingobacterium.
OX NCBI_TaxID=1010 {ECO:0000313|EMBL:SDL38234.1, ECO:0000313|Proteomes:UP000199201};
RN [1] {ECO:0000313|EMBL:SDL38234.1, ECO:0000313|Proteomes:UP000199201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11724 {ECO:0000313|EMBL:SDL38234.1,
RC ECO:0000313|Proteomes:UP000199201};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FNGK01000003; SDL38234.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239XC55; -.
DR STRING; 1010.SAMN05192578_103110; -.
DR OrthoDB; 9802808at2; -.
DR Proteomes; UP000199201; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR CDD; cd01030; TOPRIM_TopoIIA_like; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR PANTHER; PTHR45866:SF2; DNA TOPOISOMERASE (ATP-HYDROLYZING); 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:SDL38234.1}.
FT DOMAIN 402..512
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
SQ SEQUENCE 631 AA; 71373 MW; 07436CF44D1CC7D5 CRC64;
MSTYNEDSIR SLDWKEHIRL RPGMYIGKLG DGSAYDDGIY VLLKEVVDNS IDEFVMGAGK
IIDITVNENR VTVRDYGRGI PIGSVVDVVS KINTGGKYDS KAFQKSVGLN GVGTKAVNAL
SNQFSVQSYR QNVTRIAQFS KGELVSDEQK DTTQRNGTSV TFYPDDSIFR NYKYRLEFVE
NMIWNYVFLN SGLTINFNGQ RFISENGLKD LLERNVDTEG MRYPIIHLKG DDIEIAMTHG
QQYGEEYYSF VNGQHTTQGG THQAAYREAV VKTIREFYKK EFDASDVRAS IIGAIAIKVQ
EPVFESQTKT KLGSQSVGPD GPTVRTFIND FVKKALDDYL HKNPATADAL QKRIMQSERE
RKDIAGIKKL ANERAKKASL HNRKLRDCKV HFSDKHERNL ETTLFITEGD SASGSITKSR
DVYTQAVFSL KGKPLNSYGL TKKIVYENEE FNLLQHALNI EDGIEGLRYN NIVIATDADV
DGMHIRLLLM TFFLQFFPEL VKAGHVSILQ TPLFRVRNKK ETIYCYSDEE RVNAIKKLGA
KPEITRFKGL GEISPSEFGM FIGENIRLEP VILSKDNKLP QLLEYYMGKN TPDRQVHIVN
NLRVELDTED DLVTTKDGVE EAAIESIQEA V
//
