ID A0A239ZB94_CLOCO Unreviewed; 148 AA.
AC A0A239ZB94;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN Name=rnhA {ECO:0000313|EMBL:STA91725.1};
GN ORFNames=NCTC13028_00989 {ECO:0000313|EMBL:SQB34095.1}, NCTC2909_00435
GN {ECO:0000313|EMBL:STA91725.1}, SAMN05216497_12117
GN {ECO:0000313|EMBL:SDL34558.1};
OS Clostridium cochlearium.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1494 {ECO:0000313|EMBL:STA91725.1, ECO:0000313|Proteomes:UP000253892};
RN [1] {ECO:0000313|EMBL:SDL34558.1, ECO:0000313|Proteomes:UP000198811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NLAE-zl-C224 {ECO:0000313|EMBL:SDL34558.1,
RC ECO:0000313|Proteomes:UP000198811};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000250223, ECO:0000313|Proteomes:UP000253892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13028 {ECO:0000313|EMBL:SQB34095.1,
RC ECO:0000313|Proteomes:UP000250223}, and NCTC2909
RC {ECO:0000313|EMBL:STA91725.1, ECO:0000313|Proteomes:UP000253892};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage to 5'-phosphomonoester.; EC=3.1.26.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000077};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; FNGL01000021; SDL34558.1; -; Genomic_DNA.
DR EMBL; UAWC01000006; SQB34095.1; -; Genomic_DNA.
DR EMBL; UFWH01000001; STA91725.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239ZB94; -.
DR STRING; 1494.SAMN05216497_12117; -.
DR OrthoDB; 7845843at2; -.
DR Proteomes; UP000198811; Unassembled WGS sequence.
DR Proteomes; UP000250223; Unassembled WGS sequence.
DR Proteomes; UP000253892; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09278; RNase_HI_prokaryote_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR022892; RNaseHI.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:STA91725.1}.
FT DOMAIN 1..145
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 148 AA; 16845 MW; BD407E47FB5273ED CRC64;
MKKVILYTDG ACRGNGKEST IGGYGIVLIY KDVRKEIKKA FKNTTNNIME LSAVVEGLSL
LKEPCDVEVY SDSAYVVNAI NNKWIDSWLK NGWKTANKTP VKNKELWQQL IELLKKHKVK
FIKVKGHSDN ELNNRCDELA NEAMDELI
//
