ID A0A240AIG5_SERFI Unreviewed; 417 AA.
AC A0A240AIG5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Enterobactin exporter EntS {ECO:0000256|HAMAP-Rule:MF_01436};
GN Name=entS_1 {ECO:0000313|EMBL:SNV83197.1};
GN Synonyms=entS {ECO:0000256|HAMAP-Rule:MF_01436};
GN ORFNames=SAMEA4384070_00304 {ECO:0000313|EMBL:SNV83197.1};
OS Serratia ficaria.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=61651 {ECO:0000313|EMBL:SNV83197.1, ECO:0000313|Proteomes:UP000215134};
RN [1] {ECO:0000313|EMBL:SNV83197.1, ECO:0000313|Proteomes:UP000215134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12148 {ECO:0000313|EMBL:SNV83197.1,
RC ECO:0000313|Proteomes:UP000215134};
RG Pathogen Informatics;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of an export pathway for enterobactin.
CC {ECO:0000256|HAMAP-Rule:MF_01436}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_01436}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01436}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. EntS (TC
CC 2.A.1.38) family. {ECO:0000256|HAMAP-Rule:MF_01436}.
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DR EMBL; LT906479; SNV83197.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A240AIG5; -.
DR STRING; 1411141.GCA_001590885_04095; -.
DR KEGG; sfj:SAMEA4384070_0304; -.
DR OrthoDB; 7283966at2; -.
DR Proteomes; UP000215134; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042931; F:enterobactin transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR HAMAP; MF_01436; MFS_EntS; 1.
DR InterPro; IPR023722; Enterobactin_exp_EntS.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23513:SF9; ENTEROBACTIN EXPORTER ENTS; 1.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01436};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01436};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01436};
KW Reference proteome {ECO:0000313|Proteomes:UP000215134};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01436};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01436};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01436}.
FT TOPO_DOM 1..21
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 43..55
FT /note="Periplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 77..83
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 105..109
FT /note="Periplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 111..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 131..156
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 147..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 178
FT /note="Periplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TOPO_DOM 200..218
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 225..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 240..256
FT /note="Periplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 278..287
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 289..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 308..313
FT /note="Periplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 313..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 337..356
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 357..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 378
FT /note="Periplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT TRANSMEM 380..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 400..417
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01436"
FT DOMAIN 18..412
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 417 AA; 43239 MW; 4EA9E2DBE357C41E CRC64;
MSKPSILLDF GLLKSNRSFR AVFCARFISI LALGLMAIAI PVQIQALTGS TLLVGLAVTL
AGGGMFAGLL MGGVLADRYE RRRLILFARS TCGIGFVGLC VNAALPAPSL TAIYLLAVWD
GFFGAVGVTA LLAATPALVG RENIVQAGAI SMLTVRFGSI LSPAVGGLVI ANMGIAWNYG
LAAFGTLLTL LPLLSLPQLM PPPQPREHPL RALAGGFGFL FQNKVIGMVA LIGALLTMAS
AVRVLYPAMA GGWQVDASHL GFMYAAVPLG AAIGAFTSGR VAHVARPGWV MLLTAIAAFV
AIGLFGLMPW YSLALLCLVA FGYLSALNSL LQYGLIQSLT PDNFLGRING LWTAQNVVGD
ALGALLLGAM GAFMRPASSA GSFGFGAAAF GILLAFAMTG LRQVTLNKPE PQPVAEK
//
