ID   A0A240AIV1_SERFI        Unreviewed;       401 AA.
AC   A0A240AIV1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE            EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE   AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN   Name=entC_1 {ECO:0000313|EMBL:SNV83209.1};
GN   ORFNames=SAMEA4384070_00305 {ECO:0000313|EMBL:SNV83209.1};
OS   Serratia ficaria.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=61651 {ECO:0000313|EMBL:SNV83209.1, ECO:0000313|Proteomes:UP000215134};
RN   [1] {ECO:0000313|EMBL:SNV83209.1, ECO:0000313|Proteomes:UP000215134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC12148 {ECO:0000313|EMBL:SNV83209.1,
RC   ECO:0000313|Proteomes:UP000215134};
RG   Pathogen Informatics;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC         ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000799};
CC   -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC       {ECO:0000256|ARBA:ARBA00005297}.
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DR   EMBL; LT906479; SNV83209.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A240AIV1; -.
DR   STRING; 1411141.GCA_001590885_04094; -.
DR   KEGG; sfj:SAMEA4384070_0305; -.
DR   OrthoDB; 9806579at2; -.
DR   Proteomes; UP000215134; Chromosome 1.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   InterPro; IPR004561; IsoChor_synthase.
DR   NCBIfam; TIGR00543; isochor_syn; 1.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:SNV83209.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215134}.
FT   DOMAIN          134..388
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   401 AA;  43351 MW;  EAD1871DC78D0B16 CRC64;
     MDIAVKGANR KELQERADEP FGADFSPASG FFFTSPFRSL ITAGCFSRVT QPAADGADLH
     GEFQRQVRQA FAEARAAGVK EPLLCGAIPF DTRQPSALFV PHESRWFDRA AFMAGVSPAA
     SGPEIAGLAE VPTQQPFMQM VSDAVAAMKA GQLDKVVLSR LLEIETRRPV DRHALMARVI
     AQNPNGFHFH VPLERGALLG ASPELLLRQA GGHFHSNPLA GSARREADAE RDLAVGERLM
     ASEKDRHEHR IVTEGMRRVL AGRSRYLNVP QTPELLTTTT LWHLSTPIDG EVASRDESAL
     SLACLLHPTP ALCGTPTPAA HALIRQLEPF DRGLFGGIVG WCDAEGNGEW VVTIRCGTVD
     GSQVRLFAGA GIVQDSSPES EWHETGTKLS TILRAFGLNQ G
//