ID A0A240AYF1_CLOCO Unreviewed; 443 AA.
AC A0A240AYF1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Putative gluconeogenesis factor {ECO:0000256|HAMAP-Rule:MF_00973};
GN ORFNames=HMJ28_02045 {ECO:0000313|EMBL:NOH15184.1}, NCTC13028_00866
GN {ECO:0000313|EMBL:SQB33987.1}, NCTC2909_02303
GN {ECO:0000313|EMBL:STA93670.1}, SAMN05216497_10214
GN {ECO:0000313|EMBL:SDK88875.1};
OS Clostridium cochlearium.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1494 {ECO:0000313|EMBL:SQB33987.1, ECO:0000313|Proteomes:UP000250223};
RN [1] {ECO:0000313|EMBL:SDK88875.1, ECO:0000313|Proteomes:UP000198811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NLAE-zl-C224 {ECO:0000313|EMBL:SDK88875.1,
RC ECO:0000313|Proteomes:UP000198811};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000250223, ECO:0000313|Proteomes:UP000253892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13028 {ECO:0000313|EMBL:SQB33987.1,
RC ECO:0000313|Proteomes:UP000250223}, and NCTC2909
RC {ECO:0000313|EMBL:STA93670.1, ECO:0000313|Proteomes:UP000253892};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:NOH15184.1, ECO:0000313|Proteomes:UP000528432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGROS13 {ECO:0000313|EMBL:NOH15184.1,
RC ECO:0000313|Proteomes:UP000528432};
RA Gupta T.B., Jauregui R., Risson A.N., Brightwell G., Maclean P.;
RT "Draft genome sequence of Clostridium cochlearium strain AGROS13 isolated
RT from a sheep dairy farm in New Zealand.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC conditions. {ECO:0000256|HAMAP-Rule:MF_00973}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00973}.
CC -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC {ECO:0000256|HAMAP-Rule:MF_00973}.
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DR EMBL; JABFIF010000002; NOH15184.1; -; Genomic_DNA.
DR EMBL; FNGL01000002; SDK88875.1; -; Genomic_DNA.
DR EMBL; UAWC01000004; SQB33987.1; -; Genomic_DNA.
DR EMBL; UFWH01000001; STA93670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A240AYF1; -.
DR STRING; 1494.SAMN05216497_10214; -.
DR OrthoDB; 9783842at2; -.
DR Proteomes; UP000198811; Unassembled WGS sequence.
DR Proteomes; UP000250223; Unassembled WGS sequence.
DR Proteomes; UP000253892; Unassembled WGS sequence.
DR Proteomes; UP000528432; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR CDD; cd07187; YvcK_like; 1.
DR Gene3D; 3.40.50.10680; CofD-like domains; 1.
DR HAMAP; MF_00973; Gluconeogen_factor; 1.
DR InterPro; IPR002882; CofD.
DR InterPro; IPR038136; CofD-like_dom_sf.
DR InterPro; IPR010119; Gluconeogen_factor.
DR NCBIfam; TIGR01826; CofD_related; 1.
DR PANTHER; PTHR30135:SF3; GLUCONEOGENESIS FACTOR-RELATED; 1.
DR PANTHER; PTHR30135; UNCHARACTERIZED PROTEIN YVCK-RELATED; 1.
DR Pfam; PF01933; CofD; 1.
DR SUPFAM; SSF142338; CofD-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00973};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 443 AA; 49700 MW; 99B22169E2B3D5BC CRC64;
MKLIDWLRPG IKVKRWVLLA IMGILLIAFG LLEFVNHHLY SIYYIAFYIF LILIGIFVIY
ISASQGMRSI IALINKGYIN VSLDSRKLEN LIYEKRLLIK GPKIVVIGGG TGLSTMLRGL
KYYTSNITAI VTVADDGGGS GDLREDLGIL PPGDIRNCIL ALSDTEPLME DLLQYRFKDG
RLKNQSFGNL FLAAMDGISN NFEEAIKKVS SVLAVTGKVV PVTLDNMVLK AKLKNGNIVK
GESNIPEEVI KQKSRIDRMF IEPEYAKAVD DAVSAIREAD AIILGPGSLY TSVIPNLLVK
DISRELEKSH ALKIYVSNIM TQPGETEGYT VSDHIKAIFN HSRSGIIDYV IVNVGKIEKN
IKNKYCEETS HLVEIDEENI RNLNVNIIGA DFVNTKNGVV RHNSEKLASI LIETIMDKKL
LYDRKKIIEY FYLSERLKEK NKK
//
