ID A0A240CCG2_SERFI Unreviewed; 196 AA.
AC A0A240CCG2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000256|HAMAP-Rule:MF_01157};
GN Name=diaA {ECO:0000256|HAMAP-Rule:MF_01157,
GN ECO:0000313|EMBL:SNW05282.1};
GN ORFNames=SAMEA4384070_04303 {ECO:0000313|EMBL:SNW05282.1};
OS Serratia ficaria.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=61651 {ECO:0000313|EMBL:SNW05282.1, ECO:0000313|Proteomes:UP000215134};
RN [1] {ECO:0000313|EMBL:SNW05282.1, ECO:0000313|Proteomes:UP000215134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12148 {ECO:0000313|EMBL:SNW05282.1,
RC ECO:0000313|Proteomes:UP000215134};
RG Pathogen Informatics;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC via direct interactions with the DnaA initiator protein.
CC {ECO:0000256|HAMAP-Rule:MF_01157}.
CC -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000256|HAMAP-
CC Rule:MF_01157}.
CC -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01157}.
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DR EMBL; LT906479; SNW05282.1; -; Genomic_DNA.
DR RefSeq; WP_061797139.1; NZ_QTUE01000001.1.
DR AlphaFoldDB; A0A240CCG2; -.
DR STRING; 1411141.GCA_001590885_02307; -.
DR GeneID; 75029422; -.
DR KEGG; sfj:SAMEA4384070_4303; -.
DR OrthoDB; 9810929at2; -.
DR Proteomes; UP000215134; Chromosome 1.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd05006; SIS_GmhA; 1.
DR HAMAP; MF_01157; SIS_DiaA; 1.
DR InterPro; IPR023070; DiaA.
DR InterPro; IPR035461; GmhA/DiaA.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR30390:SF6; DNAA INITIATOR-ASSOCIATING PROTEIN DIAA; 1.
DR PANTHER; PTHR30390; SEDOHEPTULOSE 7-PHOSPHATE ISOMERASE / DNAA INITIATOR-ASSOCIATING FACTOR FOR REPLICATION INITIATION; 1.
DR Pfam; PF13580; SIS_2; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW Rule:MF_01157}; Reference proteome {ECO:0000313|Proteomes:UP000215134}.
FT DOMAIN 34..196
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 196 AA; 21124 MW; 9A5DCB1AD13668A6 CRC64;
MLDRIKACFT ESIQTQIAAA EALPDAISRA AMTLVQSLLN GNKILCCGNG TSAANAQHFA
ASMINRFETE RPSLPAIALN ADNVVLTAIS NDRLHDEVYA KQVRALGHTG DVLLAISTRG
NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGQQDVE IRIPSHRSAR IQEMHMLTVN
CLCDLIDNTL FPHQDD
//
