ID   A0A240DXU6_9BURK        Unreviewed;       295 AA.
AC   A0A240DXU6;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00019048, ECO:0000256|RuleBase:RU361259};
DE            EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE   AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN   ORFNames=SAMN06295945_0334 {ECO:0000313|EMBL:SNX28015.1};
OS   Polynucleobacter meluiroseus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Polynucleobacter.
OX   NCBI_TaxID=1938814 {ECO:0000313|EMBL:SNX28015.1, ECO:0000313|Proteomes:UP000218069};
RN   [1] {ECO:0000313|Proteomes:UP000218069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AP-Melu-1000-B4 {ECO:0000313|Proteomes:UP000218069};
RA   Varghese N., Submissions S.;
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC         alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC         ChEBI:CHEBI:58885; EC=2.7.7.9;
CC         Evidence={ECO:0000256|ARBA:ARBA00000872,
CC         ECO:0000256|RuleBase:RU361259};
CC   -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC       {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
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DR   EMBL; OANS01000001; SNX28015.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A240DXU6; -.
DR   OrthoDB; 9803306at2; -.
DR   Proteomes; UP000218069; Unassembled WGS sequence.
DR   GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR   CDD; cd02541; UGPase_prokaryotic; 1.
DR   InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   NCBIfam; TIGR01099; galU; 1.
DR   PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361259}.
FT   DOMAIN          15..270
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
SQ   SEQUENCE   295 AA;  32280 MW;  55276BA9BC468787 CRC64;
     MSLNTNVVTK AVFPVAGLGT RFLPATKASP KEMLNVVDKP LIQYAVEEAI AAGITEMIFV
     TGRSKRAIED HFDKSYELEA ELEAKNKTAL LEIVRSVKPS HVDCVYVRQP EALGLGHAVL
     CAEKLVRDEP FAIILADDLL DGKPAVIQQM VDVFKKQNGS VVAVEKIDPS KSSSYGIVSG
     PEVSKGIYRL DGIVEKPQPQ DAPSNLAVVG RYVLSSDIFK HIRNLKPGAG GEIQLTDAIA
     SLLKEQPVFA YEYDGVRYDC GSKLGYLKAS IEFALRHPEL SADFAEYLKS RVFLK
//