ID A0A241VSB3_9GAMM Unreviewed; 374 AA.
AC A0A241VSB3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=B9T33_05535 {ECO:0000313|EMBL:OTG81986.1};
OS Acinetobacter sp. ANC 5054.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1977877 {ECO:0000313|EMBL:OTG81986.1, ECO:0000313|Proteomes:UP000194916};
RN [1] {ECO:0000313|EMBL:OTG81986.1, ECO:0000313|Proteomes:UP000194916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANC 5054 {ECO:0000313|EMBL:OTG81986.1,
RC ECO:0000313|Proteomes:UP000194916};
RA Nemec A., Radolfova-Krizova L.;
RT "High diversity of culturable Acinetobacter species in natural soil and
RT water ecosystems.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTG81986.1}.
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DR EMBL; NEGG01000004; OTG81986.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A241VSB3; -.
DR STRING; 1977877.B9T33_05535; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000194916; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 24..342
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 374 AA; 41858 MW; EBF28C2824900002 CRC64;
MTYSPVSKNY HPDLIVEEAK NGWRIVRLNR PKSLHALDES ICTALLEVFK DFEHDRDVKA
IWLDSTTPKA FCAGGDVRKL RQLVVNDEAE TANKFFEQEY ALDLLLHNYA KPVLVWGEGY
VMGGGLGLFM AAPFRLVTPY SRLAMPEINI GLYPDVGATR FLADRGAIGL FTGLTGSIMT
AAGAYGIGWA THICDAQRDN VLDTVLNIDW DHYPAGDFRA IDDTLNSMHR PVGPGPLQNS
LDVIQSVCRG HTFEHDYESI IGLSDARSDW LRQASENLQK GSPATAALTW LLWQWGKKVH
SWNEVFELET QISEWKIRHP DFVEGVRARL VDKDLSPAWK KGSEMTLKGI LADDPPLTTI
ESWNALLKQH GVIS
//
