ID   A0A241WQU5_9GAMM        Unreviewed;       663 AA.
AC   A0A241WQU5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=B9T35_00750 {ECO:0000313|EMBL:OTG96234.1};
OS   Acinetobacter sp. ANC 3832.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=1977874 {ECO:0000313|EMBL:OTG96234.1, ECO:0000313|Proteomes:UP000194704};
RN   [1] {ECO:0000313|EMBL:OTG96234.1, ECO:0000313|Proteomes:UP000194704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ANC 3832 {ECO:0000313|EMBL:OTG96234.1,
RC   ECO:0000313|Proteomes:UP000194704};
RA   Nemec A., Radolfova-Krizova L.;
RT   "High diversity of culturable Acinetobacter species in natural soil and
RT   water ecosystems.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|ARBA:ARBA00009922}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTG96234.1}.
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DR   EMBL; NEGJ01000001; OTG96234.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A241WQU5; -.
DR   STRING; 1977874.B9T35_00750; -.
DR   OrthoDB; 5905204at2; -.
DR   Proteomes; UP000194704; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   CDD; cd17932; DEXQc_UvrD; 1.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF3; ATP-DEPENDENT HELICASE_DEOXYRIBONUCLEASE SUBUNIT B; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          8..289
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          290..550
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         29..36
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   663 AA;  76023 MW;  BE4A1B5073005946 CRC64;
     MSFATLIDEL NPQQKQAATT QNKHSLVLAG AGCGKTKTIV ARAAYLIDQG IPANQIQILT
     FTRRSASEIV ARVELALGDQ AKGLRASTFH TFCMYLLRRV PKAFGLEQFS IIDRDDQMMM
     FRLIRGKDDK KNPNALPKPK ELCDLYSFAR NTRQKLSLAL EKQHPEFLEY KDQIAEIMKE
     YEARKQARSF LDYDDILAVV ASALAQSEGL VDYVASLCQH MLVDEMQDTN PLQWALLEPL
     KDKTHLFCVG DDAQSIYGFR GADFENIHHF KERVPDAQIF KLEKNYRSTQ EILDLSNWLL
     DQSSIRYDKH LEAYRGGGVK PRMHVFPNEF DEAKWIAIDI KERHLLEGAA WQDHMVLVRS
     SFAARHIEAA CIQANIPYRF IGGMKLLETA HVKDLLSLLR VIANPLDDIA WMRFLTLWNS
     VGDVSASKLS HQLLLQPEMD VIFEKLEKFG RIPEKTLLIM KQMLVLKTEV EACVSLGVEA
     LKDQLEENYA KKDWSKRLGD FDLVKQLSSK HQQLSEFLEE YVLDPVSISE IERQSQDDVV
     TLITIHSAKG TEQKVCYVAN VSAGQYPHAR AQDNFDDVEE ERRVLYVALT RAQNELILTK
     QNLNMWAKDQ VDEQGRKIES YFLNDLTRNL CTTETHYKTR QQTVKSTLIE RQSINLDFGI
     DLD
//