ID   A0A242A782_9ENTE        Unreviewed;       216 AA.
AC   A0A242A782;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Adapter protein MecA {ECO:0000256|HAMAP-Rule:MF_01124};
GN   Name=mecA {ECO:0000256|HAMAP-Rule:MF_01124};
GN   ORFNames=A5886_001975 {ECO:0000313|EMBL:OTN76896.1};
OS   Enterococcus sp. 8G7_MSG3316.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1834191 {ECO:0000313|EMBL:OTN76896.1, ECO:0000313|Proteomes:UP000195043};
RN   [1] {ECO:0000313|EMBL:OTN76896.1, ECO:0000313|Proteomes:UP000195043}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8G7_MSG3316 {ECO:0000313|EMBL:OTN76896.1,
RC   ECO:0000313|Proteomes:UP000195043};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genomic Center for Infectious Diseases;
RA   Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA   Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Enterococcus sp. 8G7_MSG3316.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Enables the recognition and targeting of unfolded and
CC       aggregated proteins to the ClpC protease or to other proteins involved
CC       in proteolysis. {ECO:0000256|HAMAP-Rule:MF_01124}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738, ECO:0000256|HAMAP-
CC       Rule:MF_01124}.
CC   -!- DOMAIN: The N-terminal domain probably binds unfolded/aggregated
CC       proteins; the C-terminal domain interacts with ClpC.
CC       {ECO:0000256|HAMAP-Rule:MF_01124}.
CC   -!- SIMILARITY: Belongs to the MecA family. {ECO:0000256|ARBA:ARBA00005397,
CC       ECO:0000256|HAMAP-Rule:MF_01124}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTN76896.1}.
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DR   EMBL; NGKU01000001; OTN76896.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A242A782; -.
DR   STRING; 1834191.A5886_001975; -.
DR   OrthoDB; 2360201at2; -.
DR   Proteomes; UP000195043; Unassembled WGS sequence.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.1950; -; 1.
DR   HAMAP; MF_01124; MecA; 1.
DR   InterPro; IPR038471; MecA_C_sf.
DR   InterPro; IPR008681; Neg-reg_MecA.
DR   PANTHER; PTHR39161; ADAPTER PROTEIN MECA; 1.
DR   PANTHER; PTHR39161:SF1; ADAPTER PROTEIN MECA; 1.
DR   Pfam; PF05389; MecA; 1.
DR   PIRSF; PIRSF029008; MecA; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   216 AA;  24936 MW;  D2FD1B6A579328A0 CRC64;
     MEMEHINENT IRVLIKSEDL AARGITFLDL LGNHNEIENF FYSILEEVDI DEEFKGSEAV
     TFQVLPKGDG LELFISKNLP PEAMENFDDL SENEHEDITD MLKKHVVAQL QEAEQPEEIG
     TRFVFELAHF EDMIQLAAEV YLEAVASNLY QMGNQYFIEL RFTDPEVTDI EVENALSYLM
     EFAQRTAVTP EVLSEYGQLI MENDALALTR YYFKTE
//