ID A0A242APV5_9ENTE Unreviewed; 517 AA.
AC A0A242APV5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=PTS system, maltose and glucose-specific IIBC component {ECO:0000313|EMBL:OTN83092.1};
GN ORFNames=A5821_003015 {ECO:0000313|EMBL:OTN83092.1};
OS Enterococcus sp. 7F3_DIV0205.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1834189 {ECO:0000313|EMBL:OTN83092.1, ECO:0000313|Proteomes:UP000194948};
RN [1] {ECO:0000313|EMBL:OTN83092.1, ECO:0000313|Proteomes:UP000194948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7F3_DIV0205 {ECO:0000313|EMBL:OTN83092.1,
RC ECO:0000313|Proteomes:UP000194948};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genomic Center for Infectious Diseases;
RA Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus sp. 7F3_DIV0205.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTN83092.1}.
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DR EMBL; NGKX01000002; OTN83092.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A242APV5; -.
DR STRING; 1834189.A5821_003015; -.
DR OrthoDB; 9764327at2; -.
DR Proteomes; UP000194948; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR InterPro; IPR011301; PTS_Mal/Glc-sp_IIBC_component.
DR NCBIfam; TIGR00826; EIIB_glc; 1.
DR NCBIfam; TIGR02004; PTS-IIBC-malX; 1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR30009:SF20; PTS SYSTEM GLUCOSE-SPECIFIC EIICB COMPONENT-RELATED; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..423
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT DOMAIN 440..517
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT ACT_SITE 462
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 517 AA; 56542 MW; 687567BD9FC50ADD CRC64;
MKKKFSFWEF FQGIGKTFML PVALLAFMGL ILGIGSSFSS PSTIEILPFL DQPWLQVIFR
FMSTVGGFAF TYLPLLFAMA IPLGLARNEK GVAAFSGFVG YVVMNLSIHF YLTETGKLAD
PEHLREAGQG MVLGMQSIEM GVLGGIIVGI IVYLLHSKFY TIQLPDAFAF FGGARFIPII
TSLIMAIIGI IVPVIWPIFA LGINSVGFAI QKSGIFGPFL FGAGERLLLP FGLHHILVSM
IRFTEAGGTQ IVDGHSVSGA LNIFYTQLQS GSPISPAATA FLSQGKMPTF MFGLPAAALA
MYRTALPQNR HKIKGLLISG VIATFVTGIT EPIEFLFLFI APVLYGFHVI MTGLGFMLMA
LLQVVIGNTD GGVLDFLIFG ILQGTYTKWY FVLLVGALWF VVYYVVFKFA IQKFNLKTPG
RELVTEDVSE KERTYKKKGN YNGPLILDAL GGPKNIVSLD NCITRLRLVV DDMTIVSEQE
LKNQGAIGVI KLDANNLQVI IGTQVATVKN ELESLME
//
