ID A0A242DDB0_9ENTE Unreviewed; 782 AA.
AC A0A242DDB0;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=ABC transporter ATP-binding protein/permease {ECO:0000313|EMBL:OTO20487.1};
GN ORFNames=A5875_001840 {ECO:0000313|EMBL:OTO20487.1};
OS Enterococcus sp. 3H8_DIV0648.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1834178 {ECO:0000313|EMBL:OTO20487.1, ECO:0000313|Proteomes:UP000194623};
RN [1] {ECO:0000313|EMBL:OTO20487.1, ECO:0000313|Proteomes:UP000194623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3H8_DIV0648 {ECO:0000313|EMBL:OTO20487.1,
RC ECO:0000313|Proteomes:UP000194623};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genomic Center for Infectious Diseases;
RA Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus sp. 3H8_DIV0648.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Macrolide
CC exporter (TC 3.A.1.122) family. {ECO:0000256|ARBA:ARBA00038388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTO20487.1}.
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DR EMBL; NGLG01000001; OTO20487.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A242DDB0; -.
DR OrthoDB; 2079174at2; -.
DR Proteomes; UP000194623; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR017911; MacB-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42798:SF6; ABC TRANSPORTER, ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42798; LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF02687; FtsX; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:OTO20487.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 745..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..240
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 782 AA; 85765 MW; 36E6D1F0EA9F1ABE CRC64;
MLELKDIKKY YHVGDTTTKA LDGVSVAFRR QEFVAILGAS GSGKTTMLNV IGGLDNYDSG
DMVIDGKSTK TFKDADWDAY RNNSIGFVFQ SYNLISHLGI IDNVELGMTL SGVSKEEKQQ
RAEDALRRVG LADHMHKKPN QLSGGQMQRV AIARALANDP DILLCDEPTG ALDTETSVQI
MNLIQELSKE KLVIMVTHNP ELANKYADRT INFSDGRIMN DSHPHIEGKK GEQFQLKRTK
MKFMTALKLS FNNLRTKKGR TFLTAFASSI GIISIGIVLS LSSGFQKQID STQAETMAKY
PITISKTTTD QTANRNQALG SDKASGASKE NKNNIVAKIS DEDKAQHTNK IDQNYVDYIN
DIDPKLSNNI GFTRVVGMNL LRDVDGDVKP VKLSNEAPDS GPSMMSAMSS MTGMGVSSFP
TQLDKSSGNF LKDNYKLLSG EYPKENTDVV LIVDANNSTN INSLKNLGFD VKDGEKIDFD
KIVGTEFKLI NNNEYYTKIP TGNFIPNNDY KAMYDNANND TLKISGILRV KQSSTMNLLA
PGIAYSNELT SKIVKDNENS EIVKAQRDTD TNVMTNEKLD DATKDSTLAY LGGDSIPSSI
MIYPNNYKDK EEILSYLDDY NKGKKKEDKI IYTDLAGTMT ELTGGLMDAI TYVLVAFAGI
SLVTSMIMIG IITYTSVIER TKEIGVLKAL GARKKDITRV FDAETCILGV ASGTLGVVIA
YLATFPINAI LYNMTELKDV AQLNPVHGII LIIVSTVLTM IGGHIPARMA AKKDAAIALR
AE
//
