ID   A0A242K3U9_9ENTE        Unreviewed;       669 AA.
AC   A0A242K3U9;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN   ORFNames=A5888_003466 {ECO:0000313|EMBL:OTP12885.1};
OS   Enterococcus sp. 9E7_DIV0242.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1834193 {ECO:0000313|EMBL:OTP12885.1, ECO:0000313|Proteomes:UP000195141};
RN   [1] {ECO:0000313|EMBL:OTP12885.1, ECO:0000313|Proteomes:UP000195141}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9E7_DIV0242 {ECO:0000313|EMBL:OTP12885.1,
RC   ECO:0000313|Proteomes:UP000195141};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genomic Center for Infectious Diseases;
RA   Earl A., Manson A., Schwartman J., Gilmore M., Abouelleil A., Cao P.,
RA   Chapman S., Cusick C., Shea T., Young S., Neafsey D., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Enterococcus sp. 9E7_DIV0242.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cell wall biogenesis; lipoteichoic acid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004936}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTP12885.1}.
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DR   EMBL; NGMM01000006; OTP12885.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A242K3U9; -.
DR   Proteomes; UP000195141; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd16015; LTA_synthase; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR   PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195141};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        34..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        67..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          260..560
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   REGION          611..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        618..669
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   669 AA;  75498 MW;  DAD45CD9A9340538 CRC64;
     MNTILTILSA FVIILIILRL SQKISFIKIN KEKFLYSLGD TFFVWISSLF VYTVILGKTV
     ESVELPIYFA ITVVITLIFL GITMFIQSEN SLVTKKENRK KSKIQLFMLV FYSLVVFFSL
     LLYTSSIWLI NTFGPISIEQ LLYSMQTLGG TNTDQVYTFI DNPLIISVFT TYLFIKVVLL
     LWNNTILKKN EGRRVKRKQK KWTKLILPTV VFSTFAASIL LSVNTVGFAQ VKLYFGQSSM
     IETEFVDAKN TNLAFPEQKR NLIYIFAESL EGSFTSEELG GTQKNNLLQE LTDLTNEGAI
     NFSNSDKIGG AYQVPGTEYT AAGIVSQTSG MPLKAPTADL NSFGQGDIYS DGKARFLPGL
     TSIGEILEEQ GYNQTFIMGS PAIFGGRSTY LSQHGNYHLF DLQEARNREL IPQDYNHWWG
     FEDNKLFEYA KSEALALADK GEPFNLTMLT SDTHFPDGLL DDKPTPYDNQ YANVIAYSSK
     QITEFIRWCQ QQPFYENTTI VVSGDHLTMD QNFVKDFPED YERTIFNLYI NSPIQAEDNR
     SKNREFGSFD LFPTTLAALN VTISGDRLGM GTNLFSDKST VIERQTLASV RDEFTQRSEF
     YDKHILNYDE KSYNSDDESN DSSQTETTSE AVVESSTVSS TTGTIGTTPS IPVVTEEQTT
     DAVTEQVIE
//