ID A0A243PH68_9SPHN Unreviewed; 350 AA.
AC A0A243PH68;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Type III polyketide synthase {ECO:0000313|EMBL:OUC55993.1};
GN ORFNames=CA262_14805 {ECO:0000313|EMBL:OUC55993.1};
OS Sphingobium sp. GW456-12-10-14-TSB1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1987165 {ECO:0000313|EMBL:OUC55993.1, ECO:0000313|Proteomes:UP000194660};
RN [1] {ECO:0000313|EMBL:OUC55993.1, ECO:0000313|Proteomes:UP000194660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GW456-12-10-14-TSB1 {ECO:0000313|EMBL:OUC55993.1};
RA Song R., Chenine A.L., Ruprecht R.M.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUC55993.1}.
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DR EMBL; NGUN01000003; OUC55993.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A243PH68; -.
DR Proteomes; UP000194660; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
FT DOMAIN 4..210
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 222..346
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 148
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 350 AA; 36152 MW; BECCA2781AB8CA80 CRC64;
MSSTATIQAI GTAVPATDVH PAFIDWAGAR ITDPRERALF MRMAQRSGIH HRWSVLDGGG
GSPTAQGGFY GDAWPTTAQR MAIYADEAPA LAARAVAALG DQVAIDGITH LVVASCTGFT
APGIDQQLIR LLGLDPSVER LMVGYMGCYA AIVALRSARH IVRSEPGARV LVVCVELSSL
HLQANAEVEP LLAMLQFGDG AAAALVSAAP GGIALDQPFA MTVPDTAGLI RWDLGDHGFA
MHLSGEVPGA IAQALAGTVT LPVPADSVDM WAVHAGGRSI LDAVARALDL APDALDHSRA
VLRAFGNMSS ATLMFVLARI LAGQATGQGV ALAFGPGLAA EGLTFRREAP
//
