ID A0A243PHN4_9SPHN Unreviewed; 595 AA.
AC A0A243PHN4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Sensor domain-containing diguanylate cyclase {ECO:0000313|EMBL:OUC55457.1};
GN ORFNames=CA262_11760 {ECO:0000313|EMBL:OUC55457.1};
OS Sphingobium sp. GW456-12-10-14-TSB1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1987165 {ECO:0000313|EMBL:OUC55457.1, ECO:0000313|Proteomes:UP000194660};
RN [1] {ECO:0000313|EMBL:OUC55457.1, ECO:0000313|Proteomes:UP000194660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GW456-12-10-14-TSB1 {ECO:0000313|EMBL:OUC55457.1};
RA Song R., Chenine A.L., Ruprecht R.M.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUC55457.1}.
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DR EMBL; NGUN01000003; OUC55457.1; -; Genomic_DNA.
DR RefSeq; WP_026002109.1; NZ_NGUN01000003.1.
DR AlphaFoldDB; A0A243PHN4; -.
DR OrthoDB; 9812260at2; -.
DR Proteomes; UP000194660; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR007895; MASE1.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF4; TWO-COMPONENT RESPONSE REGULATOR; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF05231; MASE1; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 305..375
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 379..431
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 462..595
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 595 AA; 63968 MW; 826F065AFA57C0EE CRC64;
MQRSALRHSS SIFAPVVTGS VYFIVATMAL LISRFEGGLA FIWGANAFLM AELLTSRTRY
WPRAIMACAI ASTFATALFG MGPLAAIPMA AINVVESLIV AIICRRFVPD RRIIGSIRPL
VVFIIALCGV ANVVAGVMAA AVASFITSVP FGASWLQWYS GHVLGGLTFA PILILLLQGE
CGRWLRDTPK RVKVEAIVLL ALFTLAIVHV FFWASYPLLF APLLPLVLIA FRTGQVGAAA
SIIILAVVGG AATVQGLGPL NLVPGTVGAR VQYFQFYIAL SFLLSMLITA ELNSRRRLFL
MLHDSEARYR AIAEHSGDVV LNIGVDGIIR YASPSAAEQI GCAPDLLIGQ SAAHLVDPKD
RRIVIATHRR ALANPGVSHT VEFRSLLSGG DPQWCEMVSR AVVDERGVAS GVVSMIRDMS
RHKARQQALQ DVASHDSLTG ADSRGAFLEK LEAEILRARH GARSCLLLID IDHFKAVNDR
YGHGAGDRVL SAFVERLRPG LRGIDSIGRL GGEEFAILLV DSDIDRASMI CERLRARMVA
PIPVGEAGSE AISVTFSAGL VRLDGGSTRS AMLEAADKAL YRAKHSGRNC LRLAA
//
