ID   A0A243RA70_9ACTN        Unreviewed;       629 AA.
AC   A0A243RA70;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Big-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CA983_39465 {ECO:0000313|EMBL:OUC91539.1};
OS   Streptomyces swartbergensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=487165 {ECO:0000313|EMBL:OUC91539.1, ECO:0000313|Proteomes:UP000195105};
RN   [1] {ECO:0000313|EMBL:OUC91539.1, ECO:0000313|Proteomes:UP000195105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HMC13 {ECO:0000313|EMBL:OUC91539.1};
RA   Le Roes-Hill M., Prins A., Durrell K.A.;
RT   "Biotechnological potential of actinobacteria isolated from South African
RT   environments.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUC91539.1}.
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DR   EMBL; NGFN01000451; OUC91539.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A243RA70; -.
DR   Proteomes; UP000195105; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR   Pfam; PF12810; Gly_rich; 1.
DR   SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..629
FT                   /note="Big-1 domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038621963"
FT   TRANSMEM        597..618
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          142..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          538..584
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..584
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   629 AA;  60560 MW;  95CBB98E134E4272 CRC64;
     MHHDSVVLRR AGFRRGAAAL TFVALTAGTA LTGVPAATAA GSVALAGKTC TPTEGFSGCR
     LFDPTGAREE FQVPAGVTAL DVRAWGQGGE GTSSANGGAG GYTAGTLRVA PGERLSLAVG
     VQRFGDALGG AAGGKFAAVG GNSSGVRTSD GKPLLIAAGG GGGGYGSPES GQGGPGGGER
     GQDGTKPERG GKGAAGPTGG AGGGNGTSGA DASAGGEGGA GGSGSGGEGG GGGAGYAGGG
     GGGGTDEARG VAGSGAGGSS YVDPDRVTGA RLLSGDRVEA PARTDPFWQA SDEAVRGGIA
     EGGVNSDRAG HGRIVFQWKT SAIAELAQVS GAGQTVPPGG GADPVAVVAR DKAGNPVENA
     SVTFTVEDPD KLGAFFFVKD GADTTELAVP TDARGRAESA PLQAGNDKEG EFTVRAEAGG
     ASTVFTVKVR KASYTVTVAG GDDQRAERGE DFEEALQARV VRSGATAPAG TEVEFRVEDD
     SDDAPRFEDG EQVVRVRTDD SGKATAPTLT AGEGTGTYTV AASVGDAMTQ FAVEVVAGDG
     PSASPSPTAD PSASADPSPS PSTSTSGTTG GTGSSTTGGT STNLDGGSLA STGAGGIGLL
     LAAAAALATV GFAAFRLAPR LKLRSRDGA
//