ID   A0A243RD17_9ACTN        Unreviewed;       547 AA.
AC   A0A243RD17;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Fatty acid--CoA ligase {ECO:0000313|EMBL:OUC92554.1};
GN   ORFNames=CA983_37880 {ECO:0000313|EMBL:OUC92554.1};
OS   Streptomyces swartbergensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=487165 {ECO:0000313|EMBL:OUC92554.1, ECO:0000313|Proteomes:UP000195105};
RN   [1] {ECO:0000313|EMBL:OUC92554.1, ECO:0000313|Proteomes:UP000195105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HMC13 {ECO:0000313|EMBL:OUC92554.1};
RA   Le Roes-Hill M., Prins A., Durrell K.A.;
RT   "Biotechnological potential of actinobacteria isolated from South African
RT   environments.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUC92554.1}.
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DR   EMBL; NGFN01000402; OUC92554.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A243RD17; -.
DR   Proteomes; UP000195105; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:OUC92554.1}.
FT   DOMAIN          26..408
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          459..534
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   547 AA;  57744 MW;  3155FADFF92B31DF CRC64;
     MSSSYVFGRR AVRADTEWGS IPGLVRTAAE RYADAEAVVE GRTRITYAEL GARVERAAAA
     CLAHGIRPGD RVGIWAPNTL DWIVSALGAV SAGAVLVPLN TRFKGAEAAD VLRRSGARLL
     FVTGTFLGTS YVASLRRAAG QGPGSGPLPG LPDLEHVVVL SEDAPADFLT WKDFLASGEA
     VGTAEVRARA DAVDGSRPSD LIFTSGTTGR PKGAVITHAQ TLRAYDIWSD LAGLTRGDRY
     LIVNPFFHTF GYKAGVIACL TRGATMIPQP VFNVSTVLAN IAAERVSVLP GPPTLLQSLL
     DHPARDAHDL SALRLVVTGA AVVPLRLVER LRGELGVDTV LTAYGLSEAG GIVTMCRRGD
     DPAVIASTSG RAIPGTQVRV VNSRGEPLGP GTPGEVLVRG FNVMTGYYED EAATAEVLSE
     DGWLRTGDVG VLDAAGNLRI TDRLKDMFIV GGFNAYPAEI EQLLGLHPDV ADVAVIGVPD
     ARLGEVGRAY VVRRPGALLT ADDLIAWSRR EMANYKVPRT VEFVAELPRN ASGKVVKGAL
     RDGLLSG
//