ID A0A243SC36_9ACTN Unreviewed; 425 AA.
AC A0A243SC36;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=3-oxoacyl-ACP synthase {ECO:0000313|EMBL:OUD04876.1};
GN ORFNames=CA983_01735 {ECO:0000313|EMBL:OUD04876.1};
OS Streptomyces swartbergensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=487165 {ECO:0000313|EMBL:OUD04876.1, ECO:0000313|Proteomes:UP000195105};
RN [1] {ECO:0000313|EMBL:OUD04876.1, ECO:0000313|Proteomes:UP000195105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMC13 {ECO:0000313|EMBL:OUD04876.1};
RA Le Roes-Hill M., Prins A., Durrell K.A.;
RT "Biotechnological potential of actinobacteria isolated from South African
RT environments.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUD04876.1}.
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DR EMBL; NGFN01000005; OUD04876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A243SC36; -.
DR Proteomes; UP000195105; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 2..422
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 425 AA; 44707 MW; 44F0DC6658C20778 CRC64;
MTRRVVVTGL GAVCGLGLDW QTMWDGLCQG RSAIRAWRLP GVDDFPVRYA APVDDEAFAE
RYGADEELNR PMERRARFGL AAAGQALADA GFDASGTPGR VGTAVGSGVP ERDPHELLHA
VSEDGRPSWQ TLYARRAGLN PASGLLCTND ALAASIARRH RLRGPALNFS TACAGAAHAI
GHGLRMIRRG EVDAMLVGGA DSVLNLPTMT GLHLLGAPST SELFGDRLCR AFDRDRSGLV
AAEGAAMLVL ESEESARRRG ARVYAELAGF GSSLDAHQVT APHPEGKGAA LAMSRALADA
GVAPEQVDCV NAHGTSTPLN DPIETRAIKD VFASGEHYRK LAVTANKTML GHLIAAAGAP
ELIATVLSVR DGVVPPTLNL ENPDPACDLD YVPDKARYRE VSVAVSNSFG FGGLNASLVV
RGHEQ
//
