ID   A0A243WFL1_9BACT        Unreviewed;       590 AA.
AC   A0A243WFL1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Peptidoglycan glycosyltransferase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BXP70_07065 {ECO:0000313|EMBL:OUJ74534.1};
OS   Hymenobacter crusticola.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=1770526 {ECO:0000313|EMBL:OUJ74534.1, ECO:0000313|Proteomes:UP000194873};
RN   [1] {ECO:0000313|EMBL:OUJ74534.1, ECO:0000313|Proteomes:UP000194873}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIMBbqt21 {ECO:0000313|EMBL:OUJ74534.1};
RA   Liang Y., Feng F.;
RT   "A new Hymenobacter.";
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUJ74534.1}.
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DR   EMBL; MTSE01000003; OUJ74534.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A243WFL1; -.
DR   Proteomes; UP000194873; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194873}.
FT   DOMAIN          37..196
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          233..563
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   590 AA;  65168 MW;  44602D7147F19F24 CRC64;
     MLLAACSSPD QQQDQPAQSE REEYTRRRVV VSDSLFRGRV LDRNDSVLVA TRAQYLLKLP
     RRVLDTLALG QLLGWDSTTV RQRIADALPY GKGQFGYPVQ LRLTAAEVKR VQRDSSATVP
     NLTLITRRQR TYTTDAGAPV LGYLSSEAQI FYRQAKRYRR GRFYRLRSGG VESYYNGLLN
     GHHGYLHPLV DKQGKEHGTW AKDTAFLQGQ DLHLTLDVKL QAYAEKLMGG RRGYLVALDP
     RTGEILCSVS APVYKASTIT APDQARIRTE LLQSEDMPLL NRPAMLANPP GSVFKLVNAA
     VALQLGAISP TTGFRCDQSL VSCVHHHPSA KSLTMGLKYS CNPYFYQVMQ NLIDRMSDSL
     AVDTVAERHT NLAIWCRYVR SFGLDSVLGV DVPREAPGFL PTPAYYDKAR RTTNWTYRSI
     YSLSIGQGEI NLTGLQMANM AAIIANRGWY YTPHLVRSVG KSGPLPRFTE KHRTLIDSAN
     FAALVPGMVA VMQRGGTADA SSLADVGITV AGKTGTVQND EGDDHAAFVG FAPADNPKIA
     VAVYLENGGF GATAAAPCAV MVMEKYLRGS IAPKRKRWEK RIQNRARNGY
//