ID   A0A244E1Z1_9BURK        Unreviewed;       391 AA.
AC   A0A244E1Z1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Sugar kinase {ECO:0000313|EMBL:OUL98275.1};
GN   ORFNames=A8M77_32355 {ECO:0000313|EMBL:OUL98275.1};
OS   Variovorax sp. JS1663.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1851577 {ECO:0000313|EMBL:OUL98275.1, ECO:0000313|Proteomes:UP000195166};
RN   [1] {ECO:0000313|EMBL:OUL98275.1, ECO:0000313|Proteomes:UP000195166}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS1663 {ECO:0000313|EMBL:OUL98275.1};
RX   PubMed=28526789;
RA   Mahan K.M., Zheng H., Fida T.T., Parry R.J., Graham D.E., Spain J.C.;
RT   "A novel, iron-dependent enzyme that catalyzes the initial step in the
RT   biodegradation of N-nitroglycine by Variovorax sp. strain JS1663.";
RL   Appl. Environ. Microbiol. 83:0-0(2017).
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUL98275.1}.
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DR   EMBL; LYMK01000073; OUL98275.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A244E1Z1; -.
DR   OrthoDB; 8595273at2; -.
DR   Proteomes; UP000195166; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF13412; HTH_24; 1.
DR   Pfam; PF00480; ROK; 2.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:OUL98275.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195166};
KW   Transferase {ECO:0000313|EMBL:OUL98275.1}.
FT   DOMAIN          19..45
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50943"
SQ   SEQUENCE   391 AA;  40798 MW;  A37421937005B570 CRC64;
     MTTLGDQQLV KRINRSVLLR LLRARPGLSR ARLAAESGLT KSTVSLLVRE LLEDGWLLEA
     GAAVADGLGR PSIPLRIHAG LRALTGVEIA VETLRVVCVS LMGELLHAEA QPLASQSPRA
     VCGQAARMVA AAHKAIGALG LRPSGIGVGV PGAVDDASGQ VRFAPNLGWR QVSLLPDLVA
     ALAAEGVAQL PVQLQNDADA AALGEYEFAG GESEDPLVFV SCDVGVGAGV VLNDRLFTGA
     HGMAGEIGHT ILQVDGPLCS CGRRGCAEAF LGSRVLGSGR ADAMRGAAFL GVLLQNLWVT
     FEPRAMVVGG QSCFEHPGLL PEAIETVNRY AQSAGMRPPV VRAARYGEWA SAVGAAALAL
     HEYLRPLHPD SKARRARAAT FMSSKQQLQS A
//