ID A0A244EIN5_9BURK Unreviewed; 581 AA.
AC A0A244EIN5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Dihydroxy-acid dehydratase {ECO:0000313|EMBL:OUM04323.1};
GN ORFNames=A8M77_01035 {ECO:0000313|EMBL:OUM04323.1};
OS Variovorax sp. JS1663.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1851577 {ECO:0000313|EMBL:OUM04323.1, ECO:0000313|Proteomes:UP000195166};
RN [1] {ECO:0000313|EMBL:OUM04323.1, ECO:0000313|Proteomes:UP000195166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS1663 {ECO:0000313|EMBL:OUM04323.1};
RX PubMed=28526789;
RA Mahan K.M., Zheng H., Fida T.T., Parry R.J., Graham D.E., Spain J.C.;
RT "A novel, iron-dependent enzyme that catalyzes the initial step in the
RT biodegradation of N-nitroglycine by Variovorax sp. strain JS1663.";
RL Appl. Environ. Microbiol. 83:0-0(2017).
CC -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC {ECO:0000256|ARBA:ARBA00006486}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUM04323.1}.
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DR EMBL; LYMK01000001; OUM04323.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A244EIN5; -.
DR OrthoDB; 9807077at2; -.
DR Proteomes; UP000195166; Unassembled WGS sequence.
DR GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR InterPro; IPR042096; Dihydro-acid_dehy_C.
DR InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR InterPro; IPR037237; IlvD/EDD_N.
DR PANTHER; PTHR43183:SF1; HYPOTHETICAL DIHYDROXY-ACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00920; ILVD_EDD; 1.
DR SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR PROSITE; PS00886; ILVD_EDD_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000195166}.
SQ SEQUENCE 581 AA; 61896 MW; 806E001B685C27E7 CRC64;
MPDAPKKLRS AQWFGPADKN GFMYRSWMKN QGIPDHEFDG RPIVGICNTW SELTPCNAHF
RKLAEHVKRG ISEAGGFPVE FPVFSNGESN LRPTAMLTRN LASMDVEEAI RGNPIDAVVL
LAGCDKTTPA LLMGAASCDV PAIVVSGGPM LNGKLEGRDI GSGTAVWQLH ESLKAGEIDL
HQFLAAEGGM SRSAGTCNTM GTASTMACMA EALGVALPHN AAIPAVDARR YVLAQMSGAR
VVAMAKEGLT LSKILTREAF ENAIRVNAAI GGSTNAVIHL KAIAGRIGVD LALEDWTRIG
RGTPTLVDLL PSGRFLMEEF YYAGGLPAVL RRLGEAGLLP HPDAPTVNGR SLWDNVRDAP
SYNDEVIRPL DKPLLDDGGI CILRGNLAPR GAVLKPSAAT PELLKHRGRA VVFEDFDDYK
RRIGDESLEV DASSVLVMKN CGPRGYPGMA EVGNMGLPPK LLRQGIKDMV RISDARMSGT
AYGTVVLHVA PEAAAGGPLA AVRDGDWIEL DCEAGRLHLD VGDEELAARL AARASAQPAA
PPAARGGYAR LYVDHVLQAD EGCDFDFLVG CRGAEVPRHS H
//
