ID A0A245ZTU2_9SPHN Unreviewed; 336 AA.
AC A0A245ZTU2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=L-cysteate sulfo-lyase {ECO:0000313|EMBL:OWK33164.1};
DE EC=4.4.1.25 {ECO:0000313|EMBL:OWK33164.1};
GN Name=cuyA {ECO:0000313|EMBL:OWK33164.1};
GN ORFNames=SPDO_00380 {ECO:0000313|EMBL:OWK33164.1};
OS Sphingomonas dokdonensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=344880 {ECO:0000313|EMBL:OWK33164.1, ECO:0000313|Proteomes:UP000197290};
RN [1] {ECO:0000313|EMBL:OWK33164.1, ECO:0000313|Proteomes:UP000197290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21029 {ECO:0000313|EMBL:OWK33164.1,
RC ECO:0000313|Proteomes:UP000197290};
RA Poehlein A., Wuebbeler J.H., Steinbuechel A., Daniel R.;
RT "Genome sequence of Sphingomonas dokdonensis DSM 21029.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the ACC deaminase/D-cysteine desulfhydrase
CC family. {ECO:0000256|ARBA:ARBA00008639}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK33164.1}.
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DR EMBL; NBBI01000001; OWK33164.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A245ZTU2; -.
DR OrthoDB; 9801249at2; -.
DR Proteomes; UP000197290; Unassembled WGS sequence.
DR GO; GO:0034011; F:L-cysteate sulfo-lyase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR027278; ACCD_DCysDesulf.
DR InterPro; IPR005966; D-Cys_desShydrase.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01275; ACC_deam_rel; 1.
DR PANTHER; PTHR43780; 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED; 1.
DR PANTHER; PTHR43780:SF2; 1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR PIRSF; PIRSF006278; ACCD_DCysDesulf; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:OWK33164.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR006278-2}.
FT DOMAIN 13..318
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT ACT_SITE 76
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006278-1"
FT MOD_RES 49
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR006278-2"
SQ SEQUENCE 336 AA; 34538 MW; 3C6A84D342F012F8 CRC64;
MNLAQFARRR YTPGVTAIEP MPHLSRSLGG ATLYIKRDDQ LGLTAGGNKT RKLEFLVADA
LAQGADTLIT VGAVQSNHCR LTLAAAVREG LKCRLVLEQR VPGSYDPAAS GNNFLFDLLG
VEAVTVIEAG TDLQAAMEAV AADLAAQGRK GYIIPGGGSN ALGALGYVAC AEEILQQSFE
MGVAFDRIVV ASGSAGTHAG IVAGIIGNSA GIPVTGVNVR RPRPEQEGNV HKLACAVADL
AGVVPEVPRD AIVCLDDWVG PGYSIPTPEM VEAVRLFASH EGVLLDPVYT GKAAAGLIGL
VRSGAIGADE TVLFIHTGGA PALYAYQGIL SGAASA
//
