ID A0A246ACR4_9SPHI Unreviewed; 636 AA.
AC A0A246ACR4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=CBW18_06405 {ECO:0000313|EMBL:OWK70731.1};
OS Pedobacter sp. AJM.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=2003629 {ECO:0000313|EMBL:OWK70731.1, ECO:0000313|Proteomes:UP000198039};
RN [1] {ECO:0000313|Proteomes:UP000198039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AJM {ECO:0000313|Proteomes:UP000198039};
RA Mcnett A.J., Newman J.D.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK70731.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NHOT01000003; OWK70731.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A246ACR4; -.
DR OrthoDB; 1006965at2; -.
DR Proteomes; UP000198039; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF13287; Fn3_assoc; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000198039};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..636
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012173504"
FT DOMAIN 26..150
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 153..513
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 343
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 636 AA; 71075 MW; 3BDE43AA48C6C749 CRC64;
MNKALHVFIG VLMSISVFAQ SDPNLGIIPA PVSITRANGN FILDKTTVLV NQSIDGPRMN
DLLNAFIVNK AGFALRESKI IQPNQKSILL TSVGADQLPN EGYTIKVNSN QIVITGRGAG
LFYAVQSVMQ MMPEKTGDKI TIPAVTINDY PRFSYRGTML DVCRHFFPIS FIKKYIDQLA
YYKINTFHWH LTDDQGWRIE IKKYPKLTSV GSVRNGSIIG RYPGTGNYLT EVKGFYTQDE
AKELVKYAAE RYITIIPEIE LPGHASAAIA AYPALSCFPD RDTFVSDKTA WAGSRKGKQV
QQTWGVFDDI FVPSENTFKM LNDVLDEVIA IFPSKYIHIG GDEAPKTYWK ESPFCKALMK
EKGLKDEHEL QSYFIQTIEK HVNEKGRSII GWDEILEGGL APNATVMSWR GEAGGIAAAQ
QNHDVIMTPG SMGLYIDHQQ SESPDEPVTI GGLAPYQKIY AYDPVPKVLT ADQKKYIKGV
QANMWTEYIK TTNKIENHAF PRLMALAEIA WSPVERKDLK NFSEDRLPVH LARLDKMGVN
FWVPTPIGQR DKALNGDDFM IDLKVPVQGG KIYYSLDSSR PSENAFLYSV PFKVVVPKGE
KRVLKTIVIA PSGKRSVTTE TLLNNGAPEI KTEAKK
//
