ID A0A246ALB4_9FLAO Unreviewed; 523 AA.
AC A0A246ALB4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=CBW16_09485 {ECO:0000313|EMBL:OWK73719.1};
OS Flavobacteriaceae bacterium JJC.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=512012 {ECO:0000313|EMBL:OWK73719.1, ECO:0000313|Proteomes:UP000197808};
RN [1] {ECO:0000313|Proteomes:UP000197808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JJC {ECO:0000313|Proteomes:UP000197808};
RA Newman J.D.;
RT "Genome of Chryseobacterium haifense.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK73719.1}.
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DR EMBL; NHOS01000002; OWK73719.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A246ALB4; -.
DR OrthoDB; 9803205at2; -.
DR Proteomes; UP000197808; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}; Transmembrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00335}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00335"
FT DOMAIN 339..432
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 36..175
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 523 AA; 58314 MW; F25337BF39C1EDBC CRC64;
MTTTAIIIGI VCLVLGAVIG MLFSKSSLNT KAKFIVEDAK KNAENLIEKA NVQAESVRKE
KQLQAKEKFM ELKSQHDADI QARERKMQDA EKRIKDKENK LNDELSKTGK LEKDLDRQIA
DYGKKHEILE KKQQELDVAT AQKVEMLEKI ANYSAEEARN ELVEAMKAEA KTRAQAHVQG
IMEEANLNAK QEAKKIVIQT IQRIGTEQAI ENSVSVFNIE SDEVKGRIIG REGRNIRALE
AATGVEIIVD DTPEAILLSC FDPVRREIAR LSLHRLVTDG RIHPARIEEV VEKTKKHIEE
EIIEVGKRTV IDLGVHGLHP ELVKIVGRMK YRSSYGQNLL QHSREVANIA ATMAAELGLN
VKMAKRAGLL HDIGKVPEQE SELPHALLGM QWAEKYGENP EVVNAIGAHH DEVEMTSLLS
PIIQVADAIS GARPGARRQV LESYIQRLKD LEAAALSFDG VSSAYAIQAG RELRVMVESG
KVSDDQSSQL SYDISEKIQN ELTYPGQVRV TVIRETRSVN IAR
//
