ID A0A246JU27_9SPHN Unreviewed; 664 AA.
AC A0A246JU27;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Arachidonate 15-lipoxygenase {ECO:0000313|EMBL:OWQ96560.1};
GN ORFNames=CDQ91_10850 {ECO:0000313|EMBL:OWQ96560.1};
OS Sphingopyxis witflariensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=173675 {ECO:0000313|EMBL:OWQ96560.1, ECO:0000313|Proteomes:UP000197097};
RN [1] {ECO:0000313|EMBL:OWQ96560.1, ECO:0000313|Proteomes:UP000197097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14551 {ECO:0000313|EMBL:OWQ96560.1,
RC ECO:0000313|Proteomes:UP000197097};
RX PubMed=12508864; DOI=10.1099/ijs.0.02217-0;
RA Kampfer P., Witzenberger R., Denner E.B., Busse H.J., Neef A.;
RT "Sphingopyxis witflariensis sp. nov., isolated from activated sludge.";
RL Int. J. Syst. Evol. Microbiol. 52:2029-2034(2002).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWQ96560.1}.
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DR EMBL; NISJ01000005; OWQ96560.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A246JU27; -.
DR OrthoDB; 5912511at2; -.
DR Proteomes; UP000197097; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR GO; GO:0034440; P:lipid oxidation; IEA:InterPro.
DR Gene3D; 3.10.450.60; -; 1.
DR InterPro; IPR000907; LipOase.
DR InterPro; IPR013819; LipOase_C.
DR InterPro; IPR036226; LipOase_C_sf.
DR InterPro; IPR020833; LipOase_Fe_BS.
DR PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR PANTHER; PTHR11771:SF153; LIPOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00305; Lipoxygenase; 1.
DR PRINTS; PR00087; LIPOXYGENASE.
DR SUPFAM; SSF48484; Lipoxigenase; 1.
DR PROSITE; PS00711; LIPOXYGENASE_1; 1.
DR PROSITE; PS51393; LIPOXYGENASE_3; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000197097}.
FT DOMAIN 24..664
FT /note="Lipoxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51393"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 71664 MW; D4000FB19F54D9F8 CRC64;
MSFASPDFSS PTQVGASPLP SPDPSLPQQD TPAQQAARAA QLTAAQAVYV WTTDVPTLPG
VPLATRVPKN DTPTIAWFAI LINVGLGIVR NALTVKLGGI DKGELASLRA PYEAALAECD
AIEASTSHIA VEHSAHSGGN IFERAVGDVE NVIAAAERDK HVTQLKGYRE RIEDLMKVSE
AEAFQLGSKT PRSIEAYRAL FATLPVPGIS YRFQDDSSFA RLRVQGPNCM LITGVAGALP
ANFPLSEAKY QAVVNGDTLA SALADGRLFM LDYRPLEILD AGTYHGMAKY AWQPMALFAV
PPGGASLVPV AIQCGQDPAD YPMFTPSPAT DKLWGWEMAK LVVQVADGNY HELFAHLART
HLVTEAFAVA THRHLAEIHP IWALLVPHFE GTLFINEAAA TSLIAADGPI DHIFAGTIAS
SQMAAVDARL AFDFHGKMLP ADLAARGVGT DSALGDYPYR DDALLVWNTI HEWARQYVDL
YYASDTEVAG DTELAAWTEC LAGEAKIRDL GPVATRKQLI DVCTMVMFTA SAQHAAVNFP
QKDIMAFASA VTGAGWQAAP TGQRGHDKAG WLAMMPPMAL ALEQLNVLEL LGSVHYRPLG
DYRSNAFPYP KWFQDPRVTA EEGPLAWFQA ALVNVETKIA SRNANRVQPY PYLQPSLIPT
SINI
//
