ID A0A246K6G4_9SPHN Unreviewed; 550 AA.
AC A0A246K6G4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Heparinase {ECO:0000313|EMBL:OWR01593.1};
GN ORFNames=CDQ91_01940 {ECO:0000313|EMBL:OWR01593.1};
OS Sphingopyxis witflariensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=173675 {ECO:0000313|EMBL:OWR01593.1, ECO:0000313|Proteomes:UP000197097};
RN [1] {ECO:0000313|EMBL:OWR01593.1, ECO:0000313|Proteomes:UP000197097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14551 {ECO:0000313|EMBL:OWR01593.1,
RC ECO:0000313|Proteomes:UP000197097};
RX PubMed=12508864; DOI=10.1099/ijs.0.02217-0;
RA Kampfer P., Witzenberger R., Denner E.B., Busse H.J., Neef A.;
RT "Sphingopyxis witflariensis sp. nov., isolated from activated sludge.";
RL Int. J. Syst. Evol. Microbiol. 52:2029-2034(2002).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWR01593.1}.
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DR EMBL; NISJ01000001; OWR01593.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A246K6G4; -.
DR OrthoDB; 9763014at2; -.
DR Proteomes; UP000197097; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.70; -; 1.
DR Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR InterPro; IPR008929; Chondroitin_lyas.
DR InterPro; IPR012480; Hepar_II_III.
DR InterPro; IPR031680; Hepar_II_III_N.
DR PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR Pfam; PF07940; Hepar_II_III; 1.
DR Pfam; PF16889; Hepar_II_III_N; 1.
DR SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW Reference proteome {ECO:0000313|Proteomes:UP000197097};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 110..287
FT /note="Heparin-sulfate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16889"
SQ SEQUENCE 550 AA; 60898 MW; 82252C6F9C8580D9 CRC64;
MGRLFRTVRH LRATQIWHRL LQRLPRKGLR IGALSRPGTP ISTFAVPATR MSSLIAPGRA
CFLNREGPIG DDWDPSDFSK LWRYNLHYFD DLNAVGASDR VKWHSALIDR WIASNPPTAG
TGWEPYPTSL RIVNWIKWQL RENALDKAAL DSLALQTRWL ASRIEWHILG NHLFANAKAL
LFAGLIFSGE EAAAWRKMAC SILLRELREQ CLTDGAHFEL SPMYHLLFLE DVLDIMNIVE
AAARADRGSD VGAIVDAIDE RLPAMFSWAR TMVHPDGEIS FFNDAAFDIA STLAGLVDYA
LRLGRPAPEE PPSSRLLASS GYARLERHDA VVIADVGCVG PDYLPGHAHA DTLSFEMSLA
GRRLVVNGGT SLYESGAERL RQRGTIAHST LVLDGENSSE VWSSFRVGRR AYPQNVALDI
GDVVHLQAQH DGYRHLPGGP IHQRTWSLGA LYLDIADRIS GQGSHQAELH FHLGVGLRAR
AKDASCVEIH CSASGVFFAE MSSLSGLVLR VEADTHHPRF GASEPTQVIV IDFDSGDVDE
HRLRISWIGA
//
