ID A0A246WNU6_9BURK Unreviewed; 566 AA.
AC A0A246WNU6;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Membrane protein insertase YidC {ECO:0000256|ARBA:ARBA00015325, ECO:0000256|HAMAP-Rule:MF_01810};
DE AltName: Full=Foldase YidC {ECO:0000256|ARBA:ARBA00033342, ECO:0000256|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane integrase YidC {ECO:0000256|ARBA:ARBA00033245, ECO:0000256|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane protein YidC {ECO:0000256|HAMAP-Rule:MF_01810};
GN Name=yidC {ECO:0000256|HAMAP-Rule:MF_01810};
GN ORFNames=CEJ42_15570 {ECO:0000313|EMBL:OWY28044.1};
OS Herbaspirillum robiniae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Herbaspirillum.
OX NCBI_TaxID=2014887 {ECO:0000313|EMBL:OWY28044.1, ECO:0000313|Proteomes:UP000197596};
RN [1] {ECO:0000313|EMBL:OWY28044.1, ECO:0000313|Proteomes:UP000197596}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HZ10 {ECO:0000313|EMBL:OWY28044.1,
RC ECO:0000313|Proteomes:UP000197596};
RA Fan M., Lin Y.;
RT "Herbaspirillum phytohormonus sp. nov., isolated from the root nodule of
RT Robinia pseudoacacia in lead-zinc mine.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC complex formation of integral membrane proteins into the membrane.
CC Involved in integration of membrane proteins that insert both
CC dependently and independently of the Sec translocase complex, as well
CC as at least some lipoproteins. Aids folding of multispanning membrane
CC proteins. {ECO:0000256|HAMAP-Rule:MF_01810}.
CC -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC Specifically interacts with transmembrane segments of nascent integral
CC membrane proteins during membrane integration. {ECO:0000256|HAMAP-
CC Rule:MF_01810}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01810};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01810}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC {ECO:0000256|ARBA:ARBA00010527, ECO:0000256|HAMAP-Rule:MF_01810}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWY28044.1}.
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DR EMBL; NJGU01000008; OWY28044.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A246WNU6; -.
DR OrthoDB; 9780552at2; -.
DR Proteomes; UP000197596; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd20070; 5TM_YidC_Alb3; 1.
DR CDD; cd19961; EcYidC-like_peri; 1.
DR Gene3D; 2.70.98.90; -; 1.
DR HAMAP; MF_01810; YidC_type1; 1.
DR InterPro; IPR019998; Membr_insert_YidC.
DR InterPro; IPR028053; Membr_insert_YidC_N.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR InterPro; IPR047196; YidC_ALB_C.
DR InterPro; IPR038221; YidC_periplasmic_sf.
DR NCBIfam; TIGR03593; yidC_nterm; 1.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF65; INNER MEMBRANE PROTEIN ALBINO3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
DR Pfam; PF14849; YidC_periplas; 1.
DR PRINTS; PR00701; 60KDINNERMP.
DR PRINTS; PR01900; YIDCPROTEIN.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01810};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|HAMAP-Rule:MF_01810};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01810};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927, ECO:0000256|HAMAP-
KW Rule:MF_01810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01810};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01810};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01810}.
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01810"
FT TRANSMEM 432..459
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01810"
FT TRANSMEM 479..503
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01810"
FT TRANSMEM 524..543
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01810"
FT DOMAIN 87..358
FT /note="Membrane insertase YidC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14849"
FT DOMAIN 369..558
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
FT REGION 38..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 61870 MW; F2F9F6E15E606DCE CRC64;
MDIKRTVLWV VFSFSLLLLW DSWMRHNGHQ SMFFPSANQT QEQAAANPAA PAASPTGSPV
PQAGTAAPAS AAAVPAAGAA AAKGETITIT TDVVKADFDT VGGELKRLEL LNQRDVVDPT
KNLVLFDSAA GHTYLAESGL IGGAFPNHKT LFAAESGPRT LSNGDTVQLV FNAEQDGVKL
TKTFTFKRGS YLIDVKHTVT NTTAAAINPT LYLQLVRDGN KPGGESHFYS TFTGPAVYTE
AEKFEKLDFE KIATGKQEHV KKADNGWIAM VQHYFVSAII PPQQAQRDIY AEQVSPNLYR
VGVKLPLGTI APNASLTSDA QLYSGPTVNK TLEAIAPGLD LVRDYGHLAI IAKPIFWLMT
HIHAVVGNWG WTIILLTVLI KLVFFPLSAA SYRSMAKMKA VAPRMQAIRE RHKGDPQAMN
REMMAMYKTE KINPLGGCLP IAIQIPVFIA LYSALLASVE MRGAPWLGWI HDLTAPDTLF
GTIPYFNMPI GLLPIIMAAS MFLQTKLNPT PPDPVQAKVM MFMPLVFSFM FFFFPSGLVL
YWVTNNILSI AQQWVITKNI ESGKTK
//
