ID A0A248KKP1_9ENTR Unreviewed; 338 AA.
AC A0A248KKP1; A0A6G9RRM2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:ASG64421.1};
DE SubName: Full=Mal regulon transcriptional regulator MalI {ECO:0000313|EMBL:QIR29482.1};
GN Name=malI {ECO:0000313|EMBL:QIR29482.1};
GN ORFNames=CEW81_24330 {ECO:0000313|EMBL:ASG64421.1}, GY169_22930
GN {ECO:0000313|EMBL:QIR29482.1};
OS Kluyvera genomosp. 3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Kluyvera.
OX NCBI_TaxID=2774055 {ECO:0000313|EMBL:ASG64421.1, ECO:0000313|Proteomes:UP000197098};
RN [1] {ECO:0000313|EMBL:ASG64421.1, ECO:0000313|Proteomes:UP000197098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YDC799 {ECO:0000313|EMBL:ASG64421.1,
RC ECO:0000313|Proteomes:UP000197098};
RA Ito R., Pacey M.P., Doi Y.;
RT "Origin of plasmid-mediated fosfomycin resistance gene fosA3.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QIR29482.1, ECO:0000313|Proteomes:UP000503580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PO2S7 {ECO:0000313|EMBL:QIR29482.1,
RC ECO:0000313|Proteomes:UP000503580};
RA Singha K.M.;
RT "Whole genome PO2S7.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022114; ASG64421.1; -; Genomic_DNA.
DR EMBL; CP050321; QIR29482.1; -; Genomic_DNA.
DR RefSeq; WP_065357279.1; NZ_CP050321.1.
DR AlphaFoldDB; A0A248KKP1; -.
DR KEGG; kgo:CEW81_24330; -.
DR OrthoDB; 9798934at2; -.
DR Proteomes; UP000197098; Chromosome.
DR Proteomes; UP000503580; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000197098};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..48
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 338 AA; 37109 MW; CF88706A9E0230AD CRC64;
MKKVSIIDVA KRAGVSVSTV SLVLRQKGKI SDATIEKVQA AIHELGYVHN VAAANLRANT
SNLIGLILRD FSDSFSIKVM ASIVQELEAQ GYMVFLGQPL NEHEHLERCL LSFKQQGVAG
VIYLASDVRR DTLPAQIRQC PLPLVVVSQS PIKEKCNLVM RDNQQAASLA TRYLLERGHR
YIAYLGGQEH DLIRQQRLVG FRSTLTRLGI ATRDEFSPAC GDDTYAASVA TRQLLENNNA
ITALLCHSPD AMIGCIDGIH KVGRTVGKDV FLTQQVALIG FEDMLHINLT SPSFTYVSSA
SEETGRQAAT LMIRKLREPT LQNQAITLSG QLVPRESA
//
