ID A0A248VU72_9BURK Unreviewed; 422 AA.
AC A0A248VU72;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=3-isopropylmalate dehydratase {ECO:0000313|EMBL:ASW02423.1};
GN ORFNames=CJU94_30530 {ECO:0000313|EMBL:ASW02423.1};
OS Paraburkholderia aromaticivorans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=2026199 {ECO:0000313|EMBL:ASW02423.1, ECO:0000313|Proteomes:UP000215158};
RN [1] {ECO:0000313|Proteomes:UP000215158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BN5 {ECO:0000313|Proteomes:UP000215158};
RA Lee Y.;
RT "Identification and genetic characteristics of simultaneous BTEX- and
RT naphthalene-degrading Paraburkholderia sp. BN5 isolated from petroleum-
RT contaminated soil.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022990; ASW02423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A248VU72; -.
DR KEGG; parb:CJU94_30530; -.
DR OrthoDB; 9802769at2; -.
DR Proteomes; UP000215158; Chromosome 2.
DR GO; GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR InterPro; IPR011826; HAcnase/IPMdehydase_lsu_prok.
DR InterPro; IPR006251; Homoacnase/IPMdehydase_lsu.
DR NCBIfam; TIGR01343; hacA_fam; 1.
DR NCBIfam; TIGR02086; IPMI_arch; 1.
DR PANTHER; PTHR43822; HOMOACONITASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00330; Aconitase; 2.
DR PRINTS; PR00415; ACONITASE.
DR SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 29..286
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
FT DOMAIN 287..412
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
SQ SEQUENCE 422 AA; 45285 MW; D921D939455E719D CRC64;
MPHAQTLAQK LIAKACGRDE VAVGEIVTCD VDLAMFHDSS GPRRLQPMLD ELGAQLWDRS
RIVLVIDHYV PEADDESRRI VRIAREWAKQ QDLPHVYDSV GICHVVLPER GHLRPGMFCV
GGDSHSPTGG AFGAYMFGIG STEMLGVVVS GQIWVKVPET LRMHWHARLA RGVTAKDMML
HMIGRFGMNG GRYQAVEFCG EAVSALSMQE RMTLSNISAE MGAQAGLIAP DAMTLDYLRA
VGVTHDIDIM RWQSDADAPA ETHHFDAAAL APQVAAPHSP ENTDEVQAFG DIEVQVAYIG
ACTGAKLDDL RAAATVLKHR RVAQGVQLVV APASMRDQQA ATREGVMAIL EAAGAQVLAT
SCGACSGYGG QIPEGSTVIS TTARNFKGRM GSETAQVYLG SPYTVAASAL RGRITDPREV
LA
//
