ID A0A248YTT0_9ACTN Unreviewed; 377 AA.
AC A0A248YTT0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB {ECO:0000313|EMBL:ASW56982.1};
GN ORFNames=CIK06_26730 {ECO:0000313|EMBL:ASW56982.1};
OS Plantactinospora sp. KBS50.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Plantactinospora.
OX NCBI_TaxID=2024580 {ECO:0000313|EMBL:ASW56982.1, ECO:0000313|Proteomes:UP000216795};
RN [1] {ECO:0000313|EMBL:ASW56982.1, ECO:0000313|Proteomes:UP000216795}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS50 {ECO:0000313|EMBL:ASW56982.1,
RC ECO:0000313|Proteomes:UP000216795};
RA Juboi H., Hwang S.S., Yeo T.C., Nissom P.M.;
RT "Genome sequencing and analysis of secondary metabolite biosynthetic
RT capabilities of Plantactinospora sp. KBS50.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family.
CC {ECO:0000256|ARBA:ARBA00007228}.
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DR EMBL; CP022961; ASW56982.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A248YTT0; -.
DR KEGG; plk:CIK06_26730; -.
DR OrthoDB; 9785673at2; -.
DR Proteomes; UP000216795; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:ASW56982.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216795};
KW Transferase {ECO:0000313|EMBL:ASW56982.1}.
FT DOMAIN 135..211
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 39210 MW; 6B7028CC645E13D4 CRC64;
MAGNSQRRGR RVTPKQGATK GSGGKNRGSL AGRGRTLPAD ERPWHKGYSG TEKLPERTAW
KQEKERRTAA EEGRAPKIGK PGTKDTTWGK GGRGLAGGRA VARGAAGGGR GAPTRSGPRV
APGRRSNPAK DGPELLVGRN PVVEALRAQV PATALYVAQG IDIDDRVNEA VRTAADRGLA
IMEVSRAELD RMTGGVLHQG IGLQVPPFAY QPFDDLLAAA LEQPAPLLVA LDGVTDPRNL
GAVLRSAAAF GAHGVFVPER RAAGITATAW RTSAGAAARV PVGQVTNLTR ALKACQQAGF
MVVGLDADGE TDLYDLEAAV GPLVVVVGSE GRGLSRLVGE TCDMLVGIPM VSEVESLNAS
VAAAVTLAEI ARRRARQ
//
