ID A0A248YWR3_9ACTN Unreviewed; 325 AA.
AC A0A248YWR3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0000259|Pfam:PF00891};
GN ORFNames=CIK06_25305 {ECO:0000313|EMBL:ASW58000.1};
OS Plantactinospora sp. KBS50.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Plantactinospora.
OX NCBI_TaxID=2024580 {ECO:0000313|EMBL:ASW58000.1, ECO:0000313|Proteomes:UP000216795};
RN [1] {ECO:0000313|EMBL:ASW58000.1, ECO:0000313|Proteomes:UP000216795}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS50 {ECO:0000313|EMBL:ASW58000.1,
RC ECO:0000313|Proteomes:UP000216795};
RA Juboi H., Hwang S.S., Yeo T.C., Nissom P.M.;
RT "Genome sequencing and analysis of secondary metabolite biosynthetic
RT capabilities of Plantactinospora sp. KBS50.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022961; ASW58000.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A248YWR3; -.
DR KEGG; plk:CIK06_25305; -.
DR OrthoDB; 3804952at2; -.
DR Proteomes; UP000216795; Chromosome.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000216795};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 96..305
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 236
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 325 AA; 35963 MW; 467FC05AC8D52170 CRC64;
MFPTTAMCIS VAARHGLADV LADRALPVDE LASLTGTDPT QLGKVLRLLA EDGVFREVRA
DVFENSPLSH LLRSGYPRSQ HFMARLVGSG WLWDAWGRLA EGLATGRPGF EIAYDTSLWR
YLSRHPEEGQ VFNGAMNDFS EALSDLVAAA YPEFGESEII ADLGGGTGTY LGAVLTLYPG
IRRGILVDLE PVIEQARARA DLRPLLDQQR LQLTSGDFFE NVPADVDTYV VKQVMHSWDD
LHVARLLRRC RIVSPRARFV AAEFVRDAKS ARFVKNFDLV MSVTMNGNIR SEAQYAALFR
SAGYELTRVV PTDTAFSLLE ARPLA
//
