ID   A0A249JWS3_9ACTN        Unreviewed;       484 AA.
AC   A0A249JWS3;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Aldehyde dehydrogenase (NAD+) {ECO:0000313|EMBL:ASY08978.1};
GN   ORFNames=B1s21122_01175 {ECO:0000313|EMBL:ASY08978.1};
OS   Candidatus Nanopelagicus limnes.
OC   Bacteria; Actinomycetota; Actinomycetes; Candidatus Nanopelagicales;
OC   Candidatus Nanopelagicaceae; Nanopelagicus.
OX   NCBI_TaxID=1884634 {ECO:0000313|EMBL:ASY08978.1, ECO:0000313|Proteomes:UP000217153};
RN   [1] {ECO:0000313|Proteomes:UP000217153}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Neuenschwander S.M., Salcher M., Ghai R., Pernthaler J.;
RT   "High microdiversification within the ubiquitous acI lineage of
RT   Actinobacteria.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP016768; ASY08978.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A249JWS3; -.
DR   KEGG; abam:B1s21122_01175; -.
DR   OrthoDB; 6882680at2; -.
DR   Proteomes; UP000217153; Chromosome.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07111; ALDH_F16; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          30..477
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        258
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   484 AA;  52312 MW;  5A582FBC1B40249C CRC64;
     MSDFEYANAP ESKAIANISP SYGLFIGGKF VDPKKGKSFN TINPATEELL SKVGYGDKSD
     IDAAVRSARA AYTKIWSKMP AKERGKYLYR IARIMQERAR EFAVVETLDN GKPIRESRDT
     DIPLAAAHFF YHAGWADKLE YAGFGSKPKP LGVVGQIIPW NFPLLMLAWK IAPALAAGNT
     VVLKPAETTP LTALLFAQVC QQAGLPDGVV NIVTGDGITG AALVNHPDVN KVAFTGSTEV
     GKAIARSISA TKKTATLELG GKAANLVFED AAIDEAVEGI INGIFFNQGH VCCAGSRLII
     QENVADEVLE KLKKRMSLIR VGDPMDKNTD LGAINSKEQL NKIEEISKTG DAEGANRWSP
     DVKLPTKGFW YPPTIFTGVT QSHRIAREEI FGPVLSVLTF RTPAEAIEKA NNTMYGLSAG
     IWSDKGAKVL WAAKQLKAGV IWSNTFNKFD PASPFGGYKE SGWGREGGRH GLAGYLTSDS
     KVNK
//