ID A0A249KGF0_9ACTN Unreviewed; 511 AA.
AC A0A249KGF0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
GN ORFNames=A1sIA56_02985 {ECO:0000313|EMBL:ASY15883.1};
OS Candidatus Planktophila sulfonica.
OC Bacteria; Actinomycetota; Actinomycetes; Candidatus Nanopelagicales;
OC Candidatus Nanopelagicaceae; Planktophila.
OX NCBI_TaxID=1884904 {ECO:0000313|EMBL:ASY15883.1, ECO:0000313|Proteomes:UP000217215};
RN [1] {ECO:0000313|EMBL:ASY15883.1, ECO:0000313|Proteomes:UP000217215}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-IA-56 {ECO:0000313|EMBL:ASY15883.1};
RA Neuenschwander S.M., Salcher M., Ghai R., Pernthaler J.;
RT "High microdiversification within the ubiquitous acI lineage of
RT Actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
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DR EMBL; CP016773; ASY15883.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A249KGF0; -.
DR KEGG; psuf:A1sIA56_02985; -.
DR OrthoDB; 140919at2; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000217215; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612};
KW Reference proteome {ECO:0000313|Proteomes:UP000217215}.
SQ SEQUENCE 511 AA; 55010 MW; A9CC724E1FCD610B CRC64;
MKISGPSLSA VDRESDIYRK LRETHPRIAK KDSQTWGSKA AAEAAVRLNW IDLPEASQAL
LPQIADLVAK FSSHSRVVLC GMGGSSLGPE VIALTYKKDI FIFDSTDPNY AQHAIGSDLA
KTVVVVSSKS GSTIETSSQR ALFQSQFEKA GLSPVDHMLF VTDPDSPLDI EVRAGGYSVI
NADPNVGGRF SVLSAFGLLP SALVGAPIAD LLADARAEKS AFLEEDQAIL DVAYLLVTQA
EQYIAFTDAG STVPGLSDWI EQLIAESTGK DSIGRLPIAT EDSPRAKVGG SFTVAYAGSS
TDLTVEGPLG AHFIFWEWVT ALIGAALKID PFNQPNVTEA KEQTAACLTE WNNSVPVLTP
ACSEKSVEIF GDGQSLKDAL ATFIEDVKDG GYIAIMAYLD RRDDVKIAEL RSILAEKSGH
PTSFGWGPRF MHSTGQFHKG GQKNGSFLQI TGETSIDYEI PGRRYSLRTL LFAQAIGDNR
ALATRKYPLL RLHLQKRSAG IDEILAAARS L
//
