ID A0A249KUX7_9ACTN Unreviewed; 412 AA.
AC A0A249KUX7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=UDP-N-acetyl-D-glucosamine dehydrogenase {ECO:0000313|EMBL:ASY20499.1};
GN ORFNames=A7sIIA15_06625 {ECO:0000313|EMBL:ASY20499.1};
OS Candidatus Planktophila vernalis.
OC Bacteria; Actinomycetota; Actinomycetes; Candidatus Nanopelagicales;
OC Candidatus Nanopelagicaceae; Planktophila.
OX NCBI_TaxID=1884907 {ECO:0000313|EMBL:ASY20499.1, ECO:0000313|Proteomes:UP000217186};
RN [1] {ECO:0000313|EMBL:ASY20499.1, ECO:0000313|Proteomes:UP000217186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-IIA-15 {ECO:0000313|EMBL:ASY20499.1};
RA Neuenschwander S.M., Salcher M., Ghai R., Pernthaler J.;
RT "High microdiversification within the ubiquitous acI lineage of
RT Actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP016776; ASY20499.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A249KUX7; -.
DR KEGG; pvn:A7sIIA15_06625; -.
DR Proteomes; UP000217186; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000217186}.
FT DOMAIN 318..399
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 412 AA; 44315 MW; F67C44140A73E7C3 CRC64;
MPKGQPDEIA IIGQGYVGLP LAMSAVKAGW KVYGVDLDLG KIEKLRQGVS PVEDIQGSEI
KSALERDLYE PTADFERISQ AKVIAICVPT PLDDSLKPDL SMLRSAATSI APYLAKGTLL
VSESTSFPGT LRNVIIPIIM EHQENKSKDL KFACAPERVN PGDKVWNQGN TPRLVGGIDS
DSLESAVGFY QQICDSVVSV SSPEVAEAAK LLENTFRLVN IALVDELTQA CSAADLSVYE
VIAAANTKPY GFMAFYPGVG IGGHCIPVDH SYLTSWADSN GVSLDLTKSA SRVSRNMPSY
VAQRALSLVA GITNPKILIL GVSYKPGVAD VRETPASELK LALEDLGAQV VWHDPLVANW
EGTSSVDLNV DYDVAILATN QPGMQLNLLR NDRKPLLDCT NSKIMGKKVF NL
//
