ID A0A249L4I7_9ACTN Unreviewed; 300 AA.
AC A0A249L4I7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:ASY23884.1};
GN ORFNames=B1sIIB91_03030 {ECO:0000313|EMBL:ASY23884.1};
OS Candidatus Nanopelagicus abundans.
OC Bacteria; Actinomycetota; Actinomycetes; Candidatus Nanopelagicales;
OC Candidatus Nanopelagicaceae; Nanopelagicus.
OX NCBI_TaxID=1884916 {ECO:0000313|EMBL:ASY23884.1, ECO:0000313|Proteomes:UP000217210};
RN [1] {ECO:0000313|EMBL:ASY23884.1, ECO:0000313|Proteomes:UP000217210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-IIB-91 {ECO:0000313|EMBL:ASY23884.1};
RA Neuenschwander S.M., Salcher M., Ghai R., Pernthaler J.;
RT "High microdiversification within the ubiquitous acI lineage of
RT Actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP016779; ASY23884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A249L4I7; -.
DR KEGG; nab:B1sIIB91_03030; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000217210; Chromosome.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:ASY23884.1};
KW Hydrolase {ECO:0000313|EMBL:ASY23884.1};
KW Nuclease {ECO:0000313|EMBL:ASY23884.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000217210}.
FT DOMAIN 1..266
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 300 AA; 33262 MW; 3A634D817F6FF9E0 CRC64;
MTLMLLDSAS LWYRAYFGMP DTLVSPTGQP VNAIRGYLDM TSRLLVKYQP NRIVACLEGD
WRPSWRVELF PDYKLNRLDE EGAEEEPDTL GSQIPILLDV LDALGIPLLG VDDYEADDLM
ATFSVKQPGP VRIVTGDRDL FQLADDKRDV KIVYLAKGIS NHDLVDLKWI QDKYQIPGDR
YALFAMIRGD SSDGLPGIKG IGEKGAMVIA NLFKTMPEVM QAAAGADERL SANIRKKLLE
SSQYAAIAPK LVGCALDVAI PEMEISMPIK PKSLEKIIKL KDEFGLGASI DRIMSALNWV
//
