ID A0A249L4U5_9ACTN Unreviewed; 352 AA.
AC A0A249L4U5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Threonine aldolase {ECO:0000313|EMBL:ASY24004.1};
GN ORFNames=B1sIIB91_03675 {ECO:0000313|EMBL:ASY24004.1};
OS Candidatus Nanopelagicus abundans.
OC Bacteria; Actinomycetota; Actinomycetes; Candidatus Nanopelagicales;
OC Candidatus Nanopelagicaceae; Nanopelagicus.
OX NCBI_TaxID=1884916 {ECO:0000313|EMBL:ASY24004.1, ECO:0000313|Proteomes:UP000217210};
RN [1] {ECO:0000313|EMBL:ASY24004.1, ECO:0000313|Proteomes:UP000217210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-IIB-91 {ECO:0000313|EMBL:ASY24004.1};
RA Neuenschwander S.M., Salcher M., Ghai R., Pernthaler J.;
RT "High microdiversification within the ubiquitous acI lineage of
RT Actinobacteria.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; CP016779; ASY24004.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A249L4U5; -.
DR KEGG; nab:B1sIIB91_03675; -.
DR OrthoDB; 9774495at2; -.
DR Proteomes; UP000217210; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000217210}.
FT DOMAIN 8..292
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 205
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 352 AA; 37611 MW; 5BDEFE38DE2A143D CRC64;
MSSPVLIDLR SDTVTKPSAQ MREVMAAAEV GDDVYGEDPT INSLEERVAQ LFGKEAGLFC
PSGSLANQLS IRMLVAPGEE LITETNSHIV RAELGAGAVF SGITTRTWLA DRGLLSASDA
LNIARPDSGP YLVSTTAIAI ENTHNFGGGT VQPLDEIKKL RQESQSLGIA LHLDGARIWN
AHIASGVEFK EYGKYFDTIS VCLSKGLGAP VGSLMLSTKD RVIKARAWRK RYGGGMRQAG
LLAAAAHYAL DNNLALLKND HKRAKEIAIA IAAVAPKVIN PDHVETNIVG LDISSMKITA
AQLSEQLKAS GVLASALGPK YLRVVTHLDL TDSDIEKVNQ VLPQLLQRAL VS
//
