ID A0A249SMV5_9MOLU Unreviewed; 311 AA.
AC A0A249SMV5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=1-phosphofructokinase {ECO:0000256|ARBA:ARBA00013596, ECO:0000256|RuleBase:RU369061};
DE Short=Fru1PK {ECO:0000256|RuleBase:RU369061};
DE EC=2.7.1.56 {ECO:0000256|ARBA:ARBA00012131, ECO:0000256|RuleBase:RU369061};
DE AltName: Full=Fructose 1-phosphate kinase {ECO:0000256|ARBA:ARBA00032802, ECO:0000256|RuleBase:RU369061};
GN Name=pfkB {ECO:0000313|EMBL:ASZ08937.1};
GN ORFNames=CK556_01010 {ECO:0000313|EMBL:ASZ08937.1};
OS Mesoplasma chauliocola.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales;
OC Entomoplasmataceae; Mesoplasma.
OX NCBI_TaxID=216427 {ECO:0000313|EMBL:ASZ08937.1, ECO:0000313|Proteomes:UP000232229};
RN [1] {ECO:0000313|EMBL:ASZ08937.1, ECO:0000313|Proteomes:UP000232229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHPA-2 {ECO:0000313|EMBL:ASZ08937.1,
RC ECO:0000313|Proteomes:UP000232229};
RA Knight T.F.Jr., Citino T.;
RT "Complete Genome Sequence of Mesoplasma chauliocola.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the ATP-dependent phosphorylation of fructose-l-
CC phosphate to fructose-l,6-bisphosphate.
CC {ECO:0000256|RuleBase:RU369061}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-
CC bisphosphate + H(+); Xref=Rhea:RHEA:14213, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:32966, ChEBI:CHEBI:138881,
CC ChEBI:CHEBI:456216; EC=2.7.1.56;
CC Evidence={ECO:0000256|ARBA:ARBA00000823,
CC ECO:0000256|RuleBase:RU369061};
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU369061}.
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DR EMBL; CP023173; ASZ08937.1; -; Genomic_DNA.
DR RefSeq; WP_027875224.1; NZ_CP023173.1.
DR AlphaFoldDB; A0A249SMV5; -.
DR STRING; 1336232.GCA_000518825_00024; -.
DR KEGG; mchc:CK556_01010; -.
DR Proteomes; UP000232229; Chromosome.
DR GO; GO:0008662; F:1-phosphofructokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR CDD; cd01164; FruK_PfkB_like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR022463; 1-PFruKinase.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR017583; Tagatose/fructose_Pkinase.
DR NCBIfam; TIGR03168; 1-PFK; 1.
DR NCBIfam; TIGR03828; pfkB; 1.
DR PANTHER; PTHR46566:SF1; 1-PHOSPHOFRUCTOKINASE; 1.
DR PANTHER; PTHR46566; 1-PHOSPHOFRUCTOKINASE-RELATED; 1.
DR Pfam; PF00294; PfkB; 1.
DR PIRSF; PIRSF000535; 1PFK/6PFK/LacC; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU369061};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU369061};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU369061};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000535}.
FT DOMAIN 8..287
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 311 AA; 34346 MW; E670794AF6D233A5 CRC64;
MIYTVTLNPA LDHIIETNGF KIGETNYYNN EYMVIGGKGI NVSIVLNNLK AEVLSTGILG
SNNKAPFLEK FEENNLKNIF FINKGLTRTN LKIKNLAKAE ETELNGLGSS VSEKIINELK
DFLRVNLKPE DILVAAGSIP SGLQDNIYEE IGNIANEKNA LFILDTSKKS MINGIKAKPY
LIKPNIEEIC EILNLPFKEY SFNEICEMVK NLKQMGAQNV LLSRGSKGSY FFTSTDEIYQ
VGIAKGELVN SVGSGDSMIA GFTYGIYKKL TIEECLRFGA AAGGATAFTE WLGLKEDILN
LKEQVSVIKI K
//
