ID A0A250KLU5_9GAMM Unreviewed; 1130 AA.
AC A0A250KLU5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BBA32528.1};
GN ORFNames=sS8_0563 {ECO:0000313|EMBL:BBA32528.1};
OS Methylocaldum marinum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylocaldum.
OX NCBI_TaxID=1432792 {ECO:0000313|EMBL:BBA32528.1, ECO:0000313|Proteomes:UP000266313};
RN [1] {ECO:0000313|EMBL:BBA32528.1, ECO:0000313|Proteomes:UP000266313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S8 {ECO:0000313|EMBL:BBA32528.1,
RC ECO:0000313|Proteomes:UP000266313};
RA Takeuchi M., Kamagata Y., Hiraoka S., Oshima K., Hattori M., Iwasaki W.;
RT "Genome sequencing of Methylocaldum marinum.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP017928; BBA32528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A250KLU5; -.
DR KEGG; mmai:sS8_0563; -.
DR OrthoDB; 9787514at2; -.
DR Proteomes; UP000266313; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000266313};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 144..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 454..498
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 567..640
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 729..861
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 871..1128
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 182..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1130 AA; 124737 MW; 2BF78702ECBB667B CRC64;
MIGRHLKLAW LILNLALLVT IGAALGVGAR AVVTESAREL EWQAQQIRQF ASAALEWSRG
NMKQLHTWLE PLPVGSSFSK LEIRKKSGTV LDIRYRAPAG APFWASALPP LADAVPELPL
NSKNSLVLKL VPAPSRAASQ LAEALYPALA SGVGAILIAN LFFWMYLRRI AMGRMEQTHW
EKSVSPRLAS EPKAPRGTTL SRSDGAPAEC FERFPEAIVV CDAERRVSYA NASAQALFRH
TPAIEPGGAV FELIAPWDRS RFEEALEIRE ESEEGEEGEA RIVRIQALTA LGGIRPLDVA
ISPPATVGTE LILSLRDAST AQSVENSLEL RDQLLDMLSQ GLAIVSPRDH GEILYCNRTF
RNLLRLGVSP GGTTLPSVLA QGAEDGAVRN IQAAVEDIEP LDLSLSWRSG DHPTAKLALR
LAPLATEPAG SPSLAVILHD RTEEAVALDR IETELARYRT ILEEMPLGLC IADGEGKALF
LNARLAELTG KTRSQLVNSA VEEWLPWDAK ARGRVQYGEL TGFLSGAGQT LRVSTLLLQK
TAGKDLYAYL FDDITVFRQQ IQTAAEEAER LQLTLDSIAE GIITTNKDGF IQYLNPLARR
LTGLEGHDCV GMPIAKVLYL LDEKKRRPLA DPVLRAIRIG KTVKFRHDVL LVCDGKPELA
VDVSATPIFD RKQALIGGVV VIKDVSEQRS LTRQMKMRAS RDPLTGLVNR RELLSLLESL
QYEVDEYHRQ HSLCYMDLDK FKIVNDTCGH PAGDELLRQI SHLMGQCLRT QDVLARIGGD
EFCALLPNTK ADDARGVAER IRETVKSFRF TWDGKYFELG ISIGIVELAQ GIGVEENLSA
ADKACYVAKE RGRDLVHVSA GREPEFGKTT LAPWNERLLE AMEHDYFRFA VRQAQFLHGN
ARSAPSFHEV LLQLCEPEQT PIVASAFMPN ARRLDLVAVI ERWAISKLFA TRPQFSGPDG
RSHVYSIPLS AVTLAENSFV PFLLELSEGY GVPSSSICFE IAENDLVQNY SVVRHFMSKC
REHGYRFCLN QFGGGFSSFA YIRNLPLDFL KIDDCLTHRI EIDHLDEAIV SAIQNIAERM
DIRTIAQDVN TPSLLERLRN LGVHYAQGAA VESSTARPGV PAQGVDARCT
//
