ID   A0A250KQN3_9GAMM        Unreviewed;      1023 AA.
AC   A0A250KQN3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Transporter, AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:BBA33983.1};
GN   ORFNames=sS8_2029 {ECO:0000313|EMBL:BBA33983.1};
OS   Methylocaldum marinum.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylocaldum.
OX   NCBI_TaxID=1432792 {ECO:0000313|EMBL:BBA33983.1, ECO:0000313|Proteomes:UP000266313};
RN   [1] {ECO:0000313|EMBL:BBA33983.1, ECO:0000313|Proteomes:UP000266313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S8 {ECO:0000313|EMBL:BBA33983.1,
RC   ECO:0000313|Proteomes:UP000266313};
RA   Takeuchi M., Kamagata Y., Hiraoka S., Oshima K., Hattori M., Iwasaki W.;
RT   "Genome sequencing of Methylocaldum marinum.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP017928; BBA33983.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A250KQN3; -.
DR   KEGG; mmai:sS8_2029; -.
DR   OrthoDB; 9758297at2; -.
DR   Proteomes; UP000266313; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF14; BLL4319 PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266313};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        526..546
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        856..875
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        882..906
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        912..932
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        953..974
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        986..1009
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1023 AA;  110868 MW;  DC7F2D23A287E1FE CRC64;
     MGGFTDLFIK RPVLASVISL VILMLGLRSI LTLNVREYPE TYSSVITIST PYFGADAELV
     RGFITTPLEQ AIATAEGIDY LESTSVQGTS TIRARLLLNY DPNAAVAQII TKINQVRNRL
     PPGSEDPIVT VTPGEPTAAM YIAFYSEVLE RNQVTDYLNR AVRPRLETLI GVQEAPVLGG
     QTVAMRVWLD PKRMAAFRVT STDVRAALEA NNFIAAVGST KGPMLSISLD AATNLHSVEE
     FERLVVREDN GALIRLRDVA DVSLGAESYN TSVYFDGVPG VFIAVEAAPT ANTLDVAASV
     REVFPDIQRQ LPAGIRGVIV YDSTDFIRDS MREVLVSLAE ALTIVTGVIY LFLGSARAAL
     VPAVAMPLSL VGSLFLILVM GFTLNLLTLL ALILAIGMVV DDGIVIVENV HRHMEEGKSR
     FEATLESGRE LAAPIVAMNI VVVAVYAPIG FMTGLTGNLF TEFAFTVVGA TLISGVVGLT
     LSFMLCSKLL RRETGKRGLS RRVDAGFGWV AERYGRLLHA TLEQRGLVLL FGGVVLVACF
     FLYTAAEDEL APTEDQGFLI VQATADPNVS IDYLERWTGR VGEIIQGFDA TDHSFVINGV
     APGGGGVGSA YQAFAGMSMK DWDAREQSQF DIMPELQDRV NGVAGLQSAV FPPPALPGAG
     GGTPLQWVIG TTEETEALSD AVQRLLDRAR QSGKFDFIET DLHYDRLQVQ VEIDRGKAAD
     LGIDMQQLGG DLSSLLSEGY VNYFSVRDRS YRVIPQVERV HRLRPEQLEN YYLRARNGTL
     IPASTIVHLT QTVQPRELVR FNQLNAATLS GVPAPGVTLG EAVDFLRTAA AEILPGEYVT
     DWKGQSRQYV QESAELVTAF FLSVILIYLV LGAQFESFRD PAIMLVSVPM SLAGALLFMA
     LGVVTVNIYT QVGLLTLIGS IIRHGILLVE FANEVQRREG LDRRRAMETA AAIRLRPILM
     TTIATLVGMI PLWFASGPGA ESRFAIGFVL GAGMAIGTLF TLFVVPAYYT VIASERVGSG
     ERG
//