ID   A0A250KRR8_9GAMM        Unreviewed;       657 AA.
AC   A0A250KRR8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Heparinase {ECO:0000313|EMBL:BBA34262.1};
GN   ORFNames=sS8_2310 {ECO:0000313|EMBL:BBA34262.1};
OS   Methylocaldum marinum.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylocaldum.
OX   NCBI_TaxID=1432792 {ECO:0000313|EMBL:BBA34262.1, ECO:0000313|Proteomes:UP000266313};
RN   [1] {ECO:0000313|EMBL:BBA34262.1, ECO:0000313|Proteomes:UP000266313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S8 {ECO:0000313|EMBL:BBA34262.1,
RC   ECO:0000313|Proteomes:UP000266313};
RA   Takeuchi M., Kamagata Y., Hiraoka S., Oshima K., Hattori M., Iwasaki W.;
RT   "Genome sequencing of Methylocaldum marinum.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP017928; BBA34262.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A250KRR8; -.
DR   KEGG; mmai:sS8_2310; -.
DR   Proteomes; UP000266313; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.70; -; 1.
DR   Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR   InterPro; IPR008929; Chondroitin_lyas.
DR   InterPro; IPR012480; Hepar_II_III.
DR   PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR   PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR   Pfam; PF07940; Hepar_II_III; 1.
DR   SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266313};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..657
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012874350"
SQ   SEQUENCE   657 AA;  74192 MW;  3F2E89765ACD16CC CRC64;
     MSTRTLFLLT VLAAASAVPL QVLAYERETV SSLSDEEIRK AFAELKAGRG NFAPAREARE
     DWLRARQLSD SDPRWKSWVK ERTRELDTWM GKPRDKAGRV AGWVHDYVER KTGKLLKWSP
     KDPEPAEEGG REKFHAAWIA YNRIYNIARV QDAARLFRLT GADRYRDWAA SQLDFYADAY
     SGFPLQTWNG RARLMTQSLD EAKHGLILLE AARLLRGSVA EDRRAHWRDR LFLPMAENLR
     QSSSGDHNIA VWHAVAITLV GLEFGTPALA DFGKRDEMGI SKLLSRAVSP DYFWHEMTLS
     YQDYVVEALC QLFIGASLRG RLGEFKRELW IAQNLLIAPV VVRFSNGDAP TLNDSPPRRK
     TPNLKRWRES RRVLPTAIGL IEAQGKLGWN NLLDPPEPDP NRTDLPPVVS RRVPGLDGVL
     IRKGDWQAFL RYGQGARYHA QQESLTYELQ YKNVWLLRDS GTVGYGSPLH REYFRRAVAH
     NVPLVDGDGQ QPWPSVGQVD LFDPDGAGIT VSHAEYRRKV TASRKLAVIG DEFVDEIRIA
     RKDRSPKALG FVLNTGCSVS APGAEASAGL RLPDTQPFRR WQNWAAFRMP ERWTVTLDCQ
     GQRFALQVQG DRDQRVFVGT VPDSTAPYTR NGLYVETTGS DAVFRVAFKP LGAGAVR
//