ID A0A250V3S3_STROL Unreviewed; 323 AA.
AC A0A250V3S3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:GAX48716.1};
DE EC=1.1.1.169 {ECO:0000313|EMBL:GAX48716.1};
GN ORFNames=SO3561_00196 {ECO:0000313|EMBL:GAX48716.1};
OS Streptomyces olivochromogenes.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1963 {ECO:0000313|EMBL:GAX48716.1, ECO:0000313|Proteomes:UP000217446};
RN [1] {ECO:0000313|Proteomes:UP000217446}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 3561 {ECO:0000313|Proteomes:UP000217446};
RA Dohra H., Kodani S.;
RT "Streptomyces olivochromogenes NBRC 3561 whole genome shotgun sequence.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX48716.1}.
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DR EMBL; BDQI01000001; GAX48716.1; -; Genomic_DNA.
DR RefSeq; WP_067362063.1; NZ_KQ948451.1.
DR AlphaFoldDB; A0A250V3S3; -.
DR STRING; 1963.AQJ27_04980; -.
DR Proteomes; UP000217446; Unassembled WGS sequence.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF42; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:GAX48716.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000217446}.
FT DOMAIN 3..104
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 196..314
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 323 AA; 34258 MW; 519BBA72B41F0A53 CRC64;
MKVAVLGAGA IGAYVGAALH RAGADVHLIA RGPHLAAMRR HGVQVLSPRG DFTARAHATD
DPAEVGPVDY VLLGLKANSY AACGPLIEPL LHETTAVIAA QNGIPWWYFH RHGGPHDGHR
VESVDPDGAV SAVLAPERAI GCVVYAATEL EGPGVVRHLE GTRFSVGEPD RTLSGRCNAF
SEAMTAGGLK CPVERDLRND IWLKLLGNIS FNPISALSRA TMRQMCLHGG TRKVIEIMMT
ETLAVAEALG CEVGVSIERR LAGAERVGDH RTSTLQDLER GKPLELDVLL SAVVELADIT
GVEVPTLRTV HAISDLLALR SAA
//
