ID A0A250VE59_STROL Unreviewed; 523 AA.
AC A0A250VE59;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=NADH-quinone oxidoreductase subunit M {ECO:0000313|EMBL:GAX52467.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:GAX52467.1};
GN ORFNames=SO3561_03983 {ECO:0000313|EMBL:GAX52467.1};
OS Streptomyces olivochromogenes.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1963 {ECO:0000313|EMBL:GAX52467.1, ECO:0000313|Proteomes:UP000217446};
RN [1] {ECO:0000313|Proteomes:UP000217446}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 3561 {ECO:0000313|Proteomes:UP000217446};
RA Dohra H., Kodani S.;
RT "Streptomyces olivochromogenes NBRC 3561 whole genome shotgun sequence.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX52467.1}.
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DR EMBL; BDQI01000007; GAX52467.1; -; Genomic_DNA.
DR RefSeq; WP_067367448.1; NZ_KQ948454.1.
DR AlphaFoldDB; A0A250VE59; -.
DR STRING; 1963.AQJ27_14495; -.
DR Proteomes; UP000217446; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507:SF1; NAD(P)H-QUINONE OXIDOREDUCTASE CHAIN 4, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:GAX52467.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000217446};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..443
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 523 AA; 56095 MW; 1993A7A2850143B5 CRC64;
MSFPLLTATA ALPAVGAIAT AAVPAAQRVA AKWLALLVSL ATLVLAAIVL VRFDPGGDRY
QLTESHAWIK DFGVRYELGV DGIGVALVAL TALLIPFVIL AGWHDADPQE TGSKRWRPTQ
GFFALILAVE AMVIISFEAT DVFLFYIFFE AMLIPMYFLI GGFGDRAHEH GDDAAATQRS
YAAVKFLLYN LVGGLIMLAA VIGLYVVAGN FSLQEIVQAR ANGSLHMATN TERWLFLGFF
FAFAVKAPLW PLHTWLPNAM GEATAPVAVL ITAVVDKVGT FAMLRFCLQL FPEASKWATP
VILVLALISI IYGALLAVGQ RDIKRLVAYA SISHFGFIIL GIFAMTSQGQ SGATLYMVNH
GISTAALMLV AGFLISRRGS RLIADYGGVQ KVAPVLAGTF LIGGLATLSL PGLAPFVSEF
LVLVGAFERY PAVGIVATFG IVLAALYTLV LYQRTMTGPV KAEVAEMPDL RVRELLVVAP
LIALLIFLGV YPKPVTDIVN PAVQQTMSDV HKTDPKPEVE AAK
//
