ID A0A250WW57_9CHLO Unreviewed; 1429 AA.
AC A0A250WW57;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Exonuclease domain-containing protein {ECO:0000259|SMART:SM00479};
GN ORFNames=CEUSTIGMA_g2495.t1 {ECO:0000313|EMBL:GAX75051.1};
OS Chlamydomonas eustigma.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=1157962 {ECO:0000313|EMBL:GAX75051.1, ECO:0000313|Proteomes:UP000232323};
RN [1] {ECO:0000313|EMBL:GAX75051.1, ECO:0000313|Proteomes:UP000232323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2499 {ECO:0000313|EMBL:GAX75051.1,
RC ECO:0000313|Proteomes:UP000232323};
RA Hirooka S., Hirose Y., Kanesaki Y., Higuchi S., Fujiwara T., Onuma R.,
RA Era A., Ohbayashi R., Uzuka A., Nozaki H., Yoshikawa H., Miyagishima S.Y.;
RT "Acidophilic green algal genome provides insights into adaptation to an
RT acidic environment.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX75051.1}.
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DR EMBL; BEGY01000010; GAX75051.1; -; Genomic_DNA.
DR STRING; 1157962.A0A250WW57; -.
DR OrthoDB; 9810at2759; -.
DR Proteomes; UP000232323; Unassembled WGS sequence.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06143; PAN2_exo; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR048841; PAN2_N.
DR InterPro; IPR028881; PAN2_UCH_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR15728; DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2; 1.
DR PANTHER; PTHR15728:SF0; PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2; 1.
DR Pfam; PF20770; PAN2_N; 1.
DR Pfam; PF00929; RNase_T; 1.
DR Pfam; PF13423; UCH_1; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000232323}.
FT DOMAIN 1198..1388
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT REGION 616..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1429 AA; 154952 MW; B4B378ED07AD0B13 CRC64;
MFSSQYPWAE YGAAAPLNTY GSGISVIKFD EQHELLWSGT EYGRLINTHS PSLETYARWQ
AHPDGYPVLD LLPLQGCCLS LSSSQASLSV AGGASRFTYK HEAGSLVSCC WEPGQANSRA
LLSSSTAGTI LSLDLASGKA WNLPGEINSE DQFSFLRGPT GRGFVVAGLA SGSVSLLDVR
SKFKVESNIA AHTGGLAHMD VKSDTLATCG YWLRGGQLVV DSFVKVWDLR FNIKPIVSLP
CGSGTCCLAF HPSFSSTLAI VSMAGSFSFA DVGVGSVVQS YQVDTGGDAL TCCTMSSTGE
MLALGASGGF LHLWTDQEEP RVNYNSDYLE TPSPVPSPPE VLLQDSEPFS YAPLPHLASG
KYYLSDLAPG SRMKVGLPPR VVPESLLEGI KQVDFVGHVL NPSFSRSKGP GEASKLVASL
RNQRVQVVSD TKSGATEDRK AERMKKRLEQ GGVLLPSHYH KIEIRQQSGA RFEEFDFTYY
NRTKFAGLEN GIANCYCNAL LQALYFIPQF RSLMLAHKPE PDIEFCLTCE MHFLFCMLKT
GQGTPCQASN LLSALRQVRE TSALGLLDGV LVPPGVVLPE TQGPKAWALS RRLASLSRFL
LEHMYSMCKE LSTSNQMQQQ SGMSSSAAST GLADTSSATS SSGHTGTRLP PGPPRSGIKQ
PDPENLKLAS KLEDLVGMRY KQRMVCLSGS HVGAEKIREA RCFQIDLQYP IKQPASPTAP
GSITASNTSS MKASSPVASP TALMSSKDGG GEGAFAFDKS NATFSDILQS SLQAVHTTRA
WFDEKRSYQV VRQSRMPFQL PKVLAINCSP SELSDVAWWS TPQKDSKDAP KLPWALAITM
RPFTWHLEVQ EAGSVKELWE MRGSGNCGVS GEGCETVYYE LSGVISHIRD ADDLPETFED
VIKVSTNTNQ SSGKSGGNTS AARDEGHLVS CIKVPQQYWE EAGAESGPLH SSRASADPFS
MKGLVSPHLL APSGQVEYNT PAGSGAGRRL TTSESLAALP SFLDLPESLD DVLLGVSFQT
SSIGQDSNVT GQRITGQEAD DRLVTEVSET CPTFSSQGSA IKQESASAAM TTPWLLINDF
SLSMCPAPEV CNVYGGQKLP CLIFYTKVET EPVLEKEDMD ASAEVRQKTE PVGAAPSDAL
GATLKGQEVL AGPARPVLTP DQYQCLCSAL PLQGPQVHLL PKRFRPLNML TEAPKPGFIV
AIDSEFVALT PAADKTAALD GSVAASDGLL IKRQTRLCLA RVSVVRGEGP QAGEPFMDDH
VRMVEPVFDY LTRFSGLVKG DLDVLTSRHY LTTLKHVYLK LRYLADCGCV FVGHGMKKDF
RMINLILPAS QQIDTAELFS LRRQRKLSLR FLASYLLGIN IQGGTHDAIE DARTALWLYQ
KYMQLQREGT FEQKLAEMYR WGNHHGWEPV SLGVDGQPRR RVVNQQALC
//
