ID A0A250X476_9CHLO Unreviewed; 626 AA.
AC A0A250X476;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=CEUSTIGMA_g5135.t1 {ECO:0000313|EMBL:GAX77692.1};
OS Chlamydomonas eustigma.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=1157962 {ECO:0000313|EMBL:GAX77692.1, ECO:0000313|Proteomes:UP000232323};
RN [1] {ECO:0000313|EMBL:GAX77692.1, ECO:0000313|Proteomes:UP000232323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2499 {ECO:0000313|EMBL:GAX77692.1,
RC ECO:0000313|Proteomes:UP000232323};
RA Hirooka S., Hirose Y., Kanesaki Y., Higuchi S., Fujiwara T., Onuma R.,
RA Era A., Ohbayashi R., Uzuka A., Nozaki H., Yoshikawa H., Miyagishima S.Y.;
RT "Acidophilic green algal genome provides insights into adaptation to an
RT acidic environment.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|ARBA:ARBA00008723,
CC ECO:0000256|RuleBase:RU361203}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX77692.1}.
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DR EMBL; BEGY01000026; GAX77692.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A250X476; -.
DR STRING; 1157962.A0A250X476; -.
DR OrthoDB; 5485592at2759; -.
DR Proteomes; UP000232323; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 2.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR039331; PPA-like.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR PANTHER; PTHR22953:SF153; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000232323};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 25..626
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5011825540"
FT DOMAIN 99..209
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 219..444
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 549..592
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 626 AA; 69011 MW; 33DFC0CFE89C581E CRC64;
MLKHISSSNA IVLVLLSFSV ACLAKRGEEG AKRGEIVRKI IAEVGPSAFN YHNTTLCNPQ
IVGSYDACFN SGIRAVGNVD YNLTDPMVTF PVGGEPWGVS LTGPYPDGVT YRISWQTGNH
SIGPLDTLVA PDTASMTPVV ILTHNGKSII HKGTALTYKR AYTSAALQSL DYLSPVINHV
VLPNLKPGKK YTYMVGMDSM LSKSYTFKTL PLINIYPLRV GLTADIGQTV NSTVTRDHLI
ASKPHIILNV GDFSYADDYS VTTCDSPFGG PGGTCQPRWD AFATLWEPAW STTPVISSAG
NHEIEYSGIN ATLSPYDQVF SYPDNYPFLA WSSRYPVPGI VSDFGNINNN LYYATTVAGK
IRVIVMNNYY AFGPGTMQYS WAIDELLNKF DRSVTPWLIV MFHSPPYHTL FTHYKEMDCF
MSVYEDYFYA AGVDMVLNGH VHAYERTHPM YKYEEDTCGA VYITIGDGGN IEGPYRAFVD
QLDPLNNNAS FCSELSYNGM GPNENLAAGK MWGPSYQTAW NPPTCQTITF QPSTSVNGGA
PLVLMTNSST LGFCQNSQPL WSAHRDPSFG HGILEILSDT EMTMTWNRNI DGIMSSADGV
KLSRVSGCDG KRKSMLKKLR RQSRKM
//
