ID A0A250X6Z5_9CHLO Unreviewed; 645 AA.
AC A0A250X6Z5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=CEUSTIGMA_g6100.t1 {ECO:0000313|EMBL:GAX78662.1};
OS Chlamydomonas eustigma.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=1157962 {ECO:0000313|EMBL:GAX78662.1, ECO:0000313|Proteomes:UP000232323};
RN [1] {ECO:0000313|EMBL:GAX78662.1, ECO:0000313|Proteomes:UP000232323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2499 {ECO:0000313|EMBL:GAX78662.1,
RC ECO:0000313|Proteomes:UP000232323};
RA Hirooka S., Hirose Y., Kanesaki Y., Higuchi S., Fujiwara T., Onuma R.,
RA Era A., Ohbayashi R., Uzuka A., Nozaki H., Yoshikawa H., Miyagishima S.Y.;
RT "Acidophilic green algal genome provides insights into adaptation to an
RT acidic environment.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAX78662.1}.
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DR EMBL; BEGY01000034; GAX78662.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A250X6Z5; -.
DR STRING; 1157962.A0A250X6Z5; -.
DR OrthoDB; 315793at2759; -.
DR Proteomes; UP000232323; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR24089:SF747; MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR24089; SOLUTE CARRIER FAMILY 25; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR Pfam; PF00153; Mito_carr; 4.
DR PRINTS; PR00926; MITOCARRIER.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS50920; SOLCAR; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000232323};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 60..95
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 130..165
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 433..523
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 532..613
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 645 AA; 70806 MW; 2EDE0C6E7F681E83 CRC64;
MVAFTTRGVF TSADEDDHHD KTCNPFTSNF MFELRMQKRK ESWLNRKQAC IASMSCSSTC
SSGDLRKTFN LIDYNNKGFV TIEDLTAYAE ANGMPACYAE SFMKAVRGSN QLSSASGTVK
FQAFSKFVKS REAALRRAFD RFDTNGDGQI SVKELESSLR HIAITCPTSR CISRCNKKMA
KEMFSRIGGQ RYRSVDFCKF RQFFLLLPSE ELIVSYWMGQ GRCPDLDSRV LIHDENDATK
ASPWGHLLAG AVAGATSRTA TAPLETMRLA VMTGSIEPSG FGKVRLCHWN LPVLGRCACV
TRTFRFWEGA PVSLEPSGFG KVATCVTRTF RFWEGAPVSI EPSGFGKVRL CHWNLPVLGR
CTCVNRTFRF WEGAPVSIEP SGFGKNAAAI MEKGGGWRAL FRGNAVNVMR SAPSKALDFF
AFDTFKRMLG DSGSYLNTFL AAGLAGAASW TCLYPLEVVR SRVTCGSVPS AALAGGVNPF
RIMSHISATE GWRALYRGLG WSVAAIIPEA SICYGLHDAL KRSYKERMGG DPDVMTSLTF
GVLSAFTGQL VACPMETVSR RLQMSGAPGL DIIIKDISSA GIQNFYRGVG ASTIRLIPMA
CISFGTYELV RAALVRLEEW RLESETSNDI TQHCLPLQSD APCAS
//
