ID   A0A250XC03_9CHLO        Unreviewed;      1162 AA.
AC   A0A250XC03;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CEUSTIGMA_g7728.t1 {ECO:0000313|EMBL:GAX80290.1};
OS   Chlamydomonas eustigma.
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=1157962 {ECO:0000313|EMBL:GAX80290.1, ECO:0000313|Proteomes:UP000232323};
RN   [1] {ECO:0000313|EMBL:GAX80290.1, ECO:0000313|Proteomes:UP000232323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2499 {ECO:0000313|EMBL:GAX80290.1,
RC   ECO:0000313|Proteomes:UP000232323};
RA   Hirooka S., Hirose Y., Kanesaki Y., Higuchi S., Fujiwara T., Onuma R.,
RA   Era A., Ohbayashi R., Uzuka A., Nozaki H., Yoshikawa H., Miyagishima S.Y.;
RT   "Acidophilic green algal genome provides insights into adaptation to an
RT   acidic environment.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC       {ECO:0000256|ARBA:ARBA00006271}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAX80290.1}.
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DR   EMBL; BEGY01000050; GAX80290.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A250XC03; -.
DR   STRING; 1157962.A0A250XC03; -.
DR   OrthoDB; 168255at2759; -.
DR   Proteomes; UP000232323; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 1.10.1420.10; -; 2.
DR   Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR036678; MutS_con_dom_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF005813; MSH2; 3.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000232323}.
FT   DOMAIN          243..590
FT                   /note="DNA mismatch repair protein MutS core"
FT                   /evidence="ECO:0000259|SMART:SM00533"
FT   DOMAIN          638..818
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|SMART:SM00534"
FT   REGION          821..843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1162 AA;  125171 MW;  205FDE43B36D8D7F CRC64;
     MLEVDREYDT SRQALNSTYC YASLIENVKR EVGLAVFDPN KLEVRLVQFI EQGRGYSSTR
     LLLNSNDAAE VILVDSADNH FAFSASGVAS SVPQGMPIHR LPRRCFDDTG GLKALLSCAT
     DESEALLSHC QVHASHYLAL GAAGALLQHL GSMEGGCKVL ASKSVRVVLA GTTRHMQLDA
     GTVASLELVS PSGIAYVRSN HVGGCGGGGP LWMNYHQPAP ASRSGHFTQT GPGASSTGRR
     TLQKNDCLLH MLDFTRTTCG SRLMRASLLQ PLTDIPTLEM RYDCLEELLA DQEMAADLSQ
     ALTKLPKDLD RMCCSLVLRQ PKSNRTDPGQ RIASAVSAVI LLRNVLNMLP AFSQILHQAQ
     SPLLKAVKAT CEISGFSSMC KRIEEVLDSD AHVSKSPFMN RIQQCFAVHP GADPLLALAR
     ESFCRTTEHI HELCDHYTQR FVSNLNVKVS YSTKRGFYLI VSRSNNTDLA AGSSRTECSL
     PSCFTVLERR GGKGVSWCTT NELSALNMRL KDAERSCLAL AEQVLDSLIG ELSQHMSLLL
     RLVDNMALTD VMVAFSEASC SAPLPYCRPK LTRDGKVAIL QGRHPVLERD YNAGGCNNKP
     QVAKLNTGRF SSDGFLGSDD PPGVVVYQAN DTFLSQHCSF HIITGPTMSG KSTYLKQVAV
     LIILAQSGCF VPAQQMSLCP IHHIFSRMGT EDSIETKSSS FMVEMQEMTH ILQQATPGCL
     VLIDELGRAT STRDGISLSW AIAEYLVDKG CATLMATHYQ QLTELSRVYP CSVRHFKMQV
     NVRKDSMLDF LRKLEPTINS GRLQQIPGSV GSGCSADISQ GGGGCSGKAD DDSDDHGNIN
     PSAHHRTITT RAGVNAPIVS HCPRSEDGGD TVLDDGLLES IGGLPVVAER RVIVPLLPQH
     PSSRQTMMTL LPLPIQHHHD EASSALQHYG ITAACSLGLP SSLTDKAMRI ASHLEERERS
     GLPLVPCESQ LLVQQNKQHN VLENGESRES PSAAAAAEEG KCSDADKGRL CRSLAATSAS
     VMAGSQISSK EQGVLRPCAA ELLSSLSMTQ ISSWSAVRSV AGRLRALQQT TGCCISEGGA
     ATAGLSSGRV VATEDDNSSG LLCPNDNSTS YYQHNCAVLH SDDLVPAQPQ PCLRSYLLEL
     QSDAAAALVL PVSSKTPITP TT
//